143383-65-7

• 

• Basic information

  1. Product Name: permafloxacin
  2. Synonyms: permafloxacin;Premafloxacin;3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-[(3R)-3-[(1S)-1-(MethylaMino)ethyl]-1-pyrrolidinyl]-4-oxo-
  3. CAS NO:143383-65-7
  4. Molecular Formula: C21H26FN3O4
  5. Molecular Weight: 403.4472432
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 143383-65-7.mol
  9. Article Data: 1

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: 601.3°Cat760mmHg
  3. Flash Point: 317.4°C
  4. Appearance: /
  5. Density: 1.354g/cm³
  6. Vapor Pressure: 2.63E-15mmHg at 25°C
  7. Refractive Index: 1.615
  8. Storage Temp.: N/A
  9. Solubility: N/A
  10. Water Solubility: 7.477g/L(25 oC)
  11. CAS DataBase Reference: permafloxacin(CAS DataBase Reference)
  12. NIST Chemistry Reference: permafloxacin(143383-65-7)
  13. EPA Substance Registry System: permafloxacin(143383-65-7)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 143383-65-7(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
• Downstream Products
• Article

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• Factory Price API 99% permafloxacin 143383-65-7 GMP Manufacturer

  Cas No: 143383-65-7

• USD $ 0.1-0.1 / Gram

• 1 Gram

• 100 Metric Ton/Year

• Xi'an Xszo Chem Co., Ltd.
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• Permafloxacin

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• Dayang Chem (Hangzhou) Co.,Ltd.
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• 3-Quinolinecarboxylicacid,1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(3R)-3-[(1S)-1-(methylamino)ethyl]-1-pyrrolidinyl]-4-oxo-

  Cas No: 143383-65-7

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• Hangzhou J&H Chemical Co., Ltd.
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• permafloxacin

  Cas No: 143383-65-7

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• 10 Gram

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• TaiChem Taizhou Limited
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• 99% up by HPLC permafloxacin 143383-65-7

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• Sinoway Industrial Co., Ltd.
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• 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-[(3R)-3-[(1S)-1-(MethylaMino)ethyl]-1-pyrrolidinyl]-4-oxo-

  Cas No: 143383-65-7

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143383-65-7 Usage

Uses

Antibacterial (veterinary).

Check Digit Verification of cas no

The CAS Registry Mumber 143383-65-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,3,8 and 3 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 143383-65:
(8*1)+(7*4)+(6*3)+(5*3)+(4*8)+(3*3)+(2*6)+(1*5)=127
127 % 10 = 7
So 143383-65-7 is a valid CAS Registry Number.

InChI:InChI=1/C21H26FN3O4/c1-11(23-2)12-6-7-24(9-12)18-16(22)8-14-17(20(18)29-3)25(13-4-5-13)10-15(19(14)26)21(27)28/h8,10-13,23H,4-7,9H2,1-3H3,(H,27,28)/t11-,12+/m0/s1

143383-65-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	1-cyclopropyl-6-fluoro-8-methoxy-7-[(3R)-3-[(1S)-1-(methylamino)ethyl]pyrrolidin-1-yl]-4-oxoquinoline-3-carboxylic acid

1.2 Other means of identification

Product number	-
Other names	1-cyclopropyl-6-fluoro-8-methoxy-7-[3-(1-methylamino-ethyl)-pyrrolidin-1-yl]-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:143383-65-7 SDS

143383-65-7Upstream product

• 143408-75-7 1,1-dimethylethyl -methyl<1-(3-pyrrolidinyl)ethyl>carbamate 
• 847233-56-1 1-cyclopropyl-1,4-dihydro-6,7-difluoro-8-methoxy-4-oxo-quinoline-3-carboxylic acid difluoroborate ester 
• 143409-16-9 C₂₆H₃₃BF₃N₃O₆ 
• 143409-01-2 3R,1S-1-cyclopropyl-6-fluoro-7-[3-(1-N-tertbutoxycarbonyl-N-methylaminoethyl)-1-pyrrolidinyl]-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid 

143383-65-7Downstream Products

143383-65-7Relevant articles and documents

The synthesis and biological evaluation of novel series of nitrile-containing fluoroquinolones as antibacterial agents

Murphy, Sean T.,Case, Heather L.,Ellsworth, Edmund,Hagen, Susan,Huband, Michael,Joannides, Themis,Limberakis, Chris,Marotti, Keith R.,Ottolini, Amy M.,Rauckhorst, Mark,Starr, Jeremy,Stier, Michael,Taylor, Clarke,Zhu, Tong,Blaser, Adrian,Denny, William A.,Lu, Guo-Liang,Smaill, Jeff B.,Rivault, Freddy

, p. 2150 - 2155 (2008/02/02)

Several novel series of nitrile-containing fluoroquinolones with weakly basic amines are reported which have reduced potential for hERG (human ether-a-go-go gene) channel inhibition as measured by the dofetilide assay. The new fluoroquinolones are potent

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