143520-19-8 Usage
Description
2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE, with the CAS number 143520-19-8, is a complex carbohydrate derivative that plays a significant role in the field of organic chemistry, particularly in the synthesis of oligosaccharides. This molecule is characterized by its unique structure, which includes a tetra-O-benzyl-protected alpha-D-glucopyranosyl unit and a N,N,N',N'-tetramethylphosphorodiamidate group. The phosphorous moiety in this molecule serves as a leaving group, which is crucial for its reactivity and applications in chemical synthesis.
Uses
Used in Organic Chemistry:
2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE is used as a key intermediate in the synthesis of oligosaccharides. Its role as a glycosyl acceptor, along with the reactivity of its phosphorous leaving group, makes it a valuable compound for the construction of complex carbohydrate structures.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE is utilized for the development of novel drug candidates targeting various diseases, including cancer and infectious diseases. The ability to synthesize complex oligosaccharides using this compound can lead to the discovery of new therapeutic agents with improved efficacy and selectivity.
Used in Glycobiology Research:
2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE is also employed in glycobiology research, where it is used to study the structure, function, and biological roles of carbohydrates. 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE can be used to investigate the interactions between carbohydrates and proteins, as well as their involvement in cellular processes and signaling pathways.
Used in Material Science:
In the field of material science, 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE can be used to develop new materials with unique properties, such as self-assembling systems or stimuli-responsive materials. The ability to synthesize complex carbohydrate structures using this compound can lead to the creation of novel materials with potential applications in various industries, including biotechnology, pharmaceuticals, and nanotechnology.
Check Digit Verification of cas no
The CAS Registry Mumber 143520-19-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,5,2 and 0 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 143520-19:
(8*1)+(7*4)+(6*3)+(5*5)+(4*2)+(3*0)+(2*1)+(1*9)=98
98 % 10 = 8
So 143520-19-8 is a valid CAS Registry Number.
143520-19-8Relevant articles and documents
Oligosaccharide synthesis based on glycosyl donors and accepters carrying phosphorus-containing leaving groups
Hashimoto, Shun-Ichi,Sakamoto, Hiroki,Honda, Takeshi,Ikegami, Shiro
, p. 5181 - 5184 (2007/10/03)
Efficient synthetic strategy for oligosaccharides has been developed by exploiting the difference in anomeric reactivity between glycosyl donors and acceptors carrying phosphorus-containing leaving groups, wherein, the tetramethylphosphoroamidate group plays a pivotal role as anomeric protective group as well as leaving group.
