143759-66-4

• 

• Basic information

  1. Product Name: 1-{4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl}-3-(phenylsulfanyl)propan-2-ol
  2. Synonyms: 1-piperazineethanol, 4-[4,4-bis(4-fluorophenyl)butyl]-alpha-[(phenylthio)methyl]-
  3. CAS NO:143759-66-4
  4. Molecular Formula: C₂₉H₃₄F₂N₂OS
  5. Molecular Weight: 496.6549
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 143759-66-4.mol
  9. Article Data: 2

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: 625.2°C at 760 mmHg
  3. Flash Point: 331.9°C
  4. Appearance: N/A
  5. Density: 1.23g/cm³
  6. Vapor Pressure: 1.7E-16mmHg at 25°C
  7. Refractive Index: 1.624
  8. Storage Temp.: N/A
  9. Solubility: N/A
  10. CAS DataBase Reference: 1-{4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl}-3-(phenylsulfanyl)propan-2-ol(CAS DataBase Reference)
  11. NIST Chemistry Reference: 1-{4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl}-3-(phenylsulfanyl)propan-2-ol(143759-66-4)
  12. EPA Substance Registry System: 1-{4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl}-3-(phenylsulfanyl)propan-2-ol(143759-66-4)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 143759-66-4(Hazardous Substances Data)

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143759-66-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 143759-66-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,7,5 and 9 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 143759-66:
(8*1)+(7*4)+(6*3)+(5*7)+(4*5)+(3*9)+(2*6)+(1*6)=154
154 % 10 = 4
So 143759-66-4 is a valid CAS Registry Number.

143759-66-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	1-[4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl]-3-phenylsulfanylpropan-2-ol

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:143759-66-4 SDS

143759-66-4Upstream product

• 5631-35-6 1-[4,4-bis(4-fluorophenyl)butyl]piperazine 
• 108-98-5 thiophenol 
• 143759-57-3 1-[4,4-bis(4-fluorophenyl)butyl]-4-(2,3-epoxypropyl)piperazine 

143759-66-4Downstream Products

• 143759-68-6 1-[4,4-bis(4-fluorophenyl)butyl]-4-(2-methoxy-3-phenylthiopropyl)piperazine 

143759-66-4Relevant articles and documents

Novel diphenylalkyl piperazine derivatives with dual calcium antagonistic and antioxidative activities

Kimura, Makoto,Masuda, Tomoko,Yamada, Koji,Kubota, Nobuo,Kawakatsu, Nobuyuki,Mitani, Masaki,Kishii, Kenichi,Inazu, Masato,Namiki, Takayuki

, p. 1947 - 1950 (2007/10/03)

Two types of novel diphenylalkyl piperazine derivatives containing the thio or aminopropanol moiety substituted by phenyl or benzyl group were synthesized, and evaluated for their calcium antagonistic and antioxidative activities. These compounds showed apparent inhibitions against KCl-induced contractions in isolated rat aorta. Among them, phenylamino compound 9 and benzylamino compound 13 also possessed potent inhibitory activities against auto-oxidative lipid peroxidations in canine brain homogenates. Two representative compounds 3a and 9 were evaluated for their inhibitory activities against KCl-induced contractions in isolated canine arteries (basilar, coronary, mesenteric, and renal). Both compounds showed the most potent inhibitions to basilar artery.

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