144074-96-4 Usage
General Description
Pneumocandin C(0) is a naturally occurring cyclic peptide with antifungal properties. It is a member of the echinocandin class of drugs, which inhibit the synthesis of β-(1,3)-D-glucan in the cell walls of fungal organisms, leading to cell lysis and death. Pneumocandin C(0) is produced by the fungus Glarea lozoyensis and has been identified as the precursor to the antifungal drug caspofungin. It has been studied for its potential as a therapeutic agent in the treatment of invasive fungal infections, particularly those caused by Candida and Aspergillus species. Research into the development of pneumocandin C(0) as a pharmaceutical product is ongoing, with the aim of harnessing its antifungal properties for clinical use.
Check Digit Verification of cas no
The CAS Registry Mumber 144074-96-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,0,7 and 4 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 144074-96:
(8*1)+(7*4)+(6*4)+(5*0)+(4*7)+(3*4)+(2*9)+(1*6)=124
124 % 10 = 4
So 144074-96-4 is a valid CAS Registry Number.
InChI:InChI=1/C50H80N8O17/c1-5-25(2)18-26(3)12-10-8-6-7-9-11-13-38(66)52-32-21-36(64)47(72)56-46(71)34-20-31(62)24-58(34)50(75)40(35(63)22-37(51)65)54-48(73)41(43(68)42(67)28-14-16-29(60)17-15-28)55-45(70)33-19-30(61)23-57(33)49(74)39(27(4)59)53-44(32)69/h14-17,25-27,30-36,39-43,47,59-64,67-68,72H,5-13,18-24H2,1-4H3,(H2,51,65)(H,52,66)(H,53,69)(H,54,73)(H,55,70)(H,56,71)/t25?,26?,27-,30-,31-,32?,33+,34+,35-,36+,39+,40+,41+,42-,43?,47-/m1/s1
144074-96-4Relevant articles and documents
Stationary phases and a purification process using the stationary phases
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Page/Page column 7-8, (2008/06/13)
This invention relates to a novel stationary phase of Formula I and a method for purifying a peptide or lipopeptide in liquid chromatography using select stationary phases, including the stationary phases of Formula I to improve the resolution and/or productivity of the purification. This chromatographic method can be used for either an analytical or preparative scale purification.
