144223-29-0 Usage
Description
1-(2-PYRIDYLCARBONYL)BENZOTRIAZOLE 97 is an organic compound with the molecular formula C12H8N4. It is a derivative of benzotriazole, featuring a pyridylcarbonyl group attached to the benzene ring. 1-(2-PYRIDYLCARBONYL)BENZOTRIAZOLE 97 is known for its versatile chemical properties and potential applications in various fields.
Uses
Used in Chemical Synthesis:
1-(2-PYRIDYLCARBONYL)BENZOTRIAZOLE 97 is used as a reactant for the preparation of ruthenium(II) benzotriazole triphenylphosphine pyridylcarboxylato chloro complex. This complex is an important compound in the field of coordination chemistry and has potential applications in catalysis and materials science.
1-(2-PYRIDYLCARBONYL)BENZOTRIAZOLE 97 is also used as a reactant for the preparation of acyl azides via reactions with sodium azide. Acyl azides are valuable intermediates in organic synthesis, particularly for the synthesis of various heterocyclic compounds and peptides.
In addition, 1-(2-PYRIDYLCARBONYL)BENZOTRIAZOLE 97 is used as a reactant for the acylation of Grignard and heteroaryllithium reagents. This reaction is a key step in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and natural products.
Furthermore, 1-(2-PYRIDYLCARBONYL)BENZOTRIAZOLE 97 is used in chemoselective reduction reactions. These reactions are essential in organic synthesis, as they allow for the selective reduction of specific functional groups in a molecule, preserving the integrity of other sensitive groups.
Synthesis Reference(s)
Tetrahedron, 48, p. 7817, 1992 DOI: 10.1016/S0040-4020(01)80459-2
Check Digit Verification of cas no
The CAS Registry Mumber 144223-29-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,2,2 and 3 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 144223-29:
(8*1)+(7*4)+(6*4)+(5*2)+(4*2)+(3*3)+(2*2)+(1*9)=100
100 % 10 = 0
So 144223-29-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H8N4O/c17-12(10-6-3-4-8-13-10)16-11-7-2-1-5-9(11)14-15-16/h1-8H
144223-29-0Relevant articles and documents
Sulfonyl derivatives of benzotriazole: Part 1. A novel approach to the activation of carboxylic acids
Katritzky, Alan R.,Shobana,Pernak, Juliusz,Afridi,Fan, Wei-Qiang
, p. 7817 - 7822 (1992)
1-Acylbenzotriazoles (8, R = Me, Et, n-Bu and Ph) are prepared in good yields by fusion of benzotriazole and acid chlorides at 80 - 100°C. In cases when the corresponding acid chlorides are not available, 1-acylbenzotriazoles are conveniently available from 1-(1-methanesulfonyl) benzotriazole and the respective carboxylic acids as illustrated by the preparation of 2-, 3-, and 4-pyridoyl-, 2-pyrrolylcarbonyl- and 2-furoyl-benzotriazole in yields of 80 - 95%. Preparations of two sulfonyl derivatives of benzotriazole are also described.
An Improved Synthesis of Polyfunctional Acyl Azides in PEG 400
Widyan, Khalid
, p. 120 - 126 (2021/03/16)
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Preparation of polyfunctional acyl azides
Katritzky, Alan R.,Widyan, Khalid,Kirichenko, Kostyantyn
, p. 5802 - 5804 (2008/02/09)
(Chemical Equation Presented) A general synthesis of acyl azides from the corresponding N-acyl benzotriazoles is described. The procedure affords acyl azides in good yields and avoids the use of acid activators and NO+ equivalents typically emp
Regiospecific C-acylation of pyrroles and indoles using N-acylbenzotriazoles
Katritzky, Alan R.,Suzuki, Kazuyuki,Singh, Sandeep K.,He, Hai-Ying
, p. 5720 - 5723 (2007/10/03)
Reactions of pyrrole (2) or 1-methylpyrrole (4) with readily available N-acylbenzotriazoles 1a - g (RCOBt, where R = 4-tolyl, 4-nitrophenyl, 4-diethylaminophenyl, 2-furyl, 2-pyridyl, 2-indolyl, or 2-pyrrolyl) in the presence of TiCl4 produced 2
