144223-29-0Relevant articles and documents
Sulfonyl derivatives of benzotriazole: Part 1. A novel approach to the activation of carboxylic acids
Katritzky, Alan R.,Shobana,Pernak, Juliusz,Afridi,Fan, Wei-Qiang
, p. 7817 - 7822 (1992)
1-Acylbenzotriazoles (8, R = Me, Et, n-Bu and Ph) are prepared in good yields by fusion of benzotriazole and acid chlorides at 80 - 100°C. In cases when the corresponding acid chlorides are not available, 1-acylbenzotriazoles are conveniently available from 1-(1-methanesulfonyl) benzotriazole and the respective carboxylic acids as illustrated by the preparation of 2-, 3-, and 4-pyridoyl-, 2-pyrrolylcarbonyl- and 2-furoyl-benzotriazole in yields of 80 - 95%. Preparations of two sulfonyl derivatives of benzotriazole are also described.
Continuous flow hydrogenation with Pd complexes of pyridine-benzotriazole ligands
Y?lmaz, Filiz,Hür, Deniz
, (2021/08/03)
The use of continuous flow systems in chemical synthesis provides great advantages in terms of sustainability, efficiency, and safety. The ability to control reaction parameters such as temperature, pressure, and catalyst exposure in flow system enables rapid optimization of reaction conditions. In the present study, palladium complexes of 1-(piridin-2-il)-1H-benzo[d][1,2,3]triazol, N-((1H-benzo[d][1,2,3]triazol-1-il)metil)piridin-2-amin, and (1H-benzo[d][1,2,3]triazol-1-yl)(pyridin-2-yl)methanone ligands were synthesized and characterized. The catalytic activities of complexes are investigated in the hydrogenation of various alkenes such as styrene, cyclohexene, and 1-octene under continuous flow conditions. The complexes showed very high activity at 10-bar H2 pressure and 50°C for short periods of 5–10?min. The catalysts reused for 10 cycles with no significant loss of catalytic activity.
Preparation of polyfunctional acyl azides
Katritzky, Alan R.,Widyan, Khalid,Kirichenko, Kostyantyn
, p. 5802 - 5804 (2008/02/09)
(Chemical Equation Presented) A general synthesis of acyl azides from the corresponding N-acyl benzotriazoles is described. The procedure affords acyl azides in good yields and avoids the use of acid activators and NO+ equivalents typically emp
Regiospecific C-acylation of pyrroles and indoles using N-acylbenzotriazoles
Katritzky, Alan R.,Suzuki, Kazuyuki,Singh, Sandeep K.,He, Hai-Ying
, p. 5720 - 5723 (2007/10/03)
Reactions of pyrrole (2) or 1-methylpyrrole (4) with readily available N-acylbenzotriazoles 1a - g (RCOBt, where R = 4-tolyl, 4-nitrophenyl, 4-diethylaminophenyl, 2-furyl, 2-pyridyl, 2-indolyl, or 2-pyrrolyl) in the presence of TiCl4 produced 2
