144254-93-3Relevant articles and documents
SOME REACTIONS OF 3-AMINO-2-CARBOETHOXY-4,6-DIMETHYLTHIENOPYRIDINE. SYNTHESIS OF SOME NEW THIENOPYRIDINOPYRIMIDINES
Hassan, Kh. M.,El-Dean, A.M. Kamal,Youssef, M. S. K.,Atta, F. M.,Abbady, M. S.
, p. 283 - 289 (2007/10/02)
Thienopyridine oxazinone (1) has been prepared and explored as a precursor by its reaction with some reagents namely, ammonium acetate, aliphatic amines, aromatic amines, hydrazine hydrate, thiosemicarbazide, and ethyl glycinate to give pyridothienopyrimidines (II-VII).The pyrimidinone compound (II) was converted to the 4-chloro derivative (X) by its reaction with excess POCl3.Interaction of the 4-chlorocompound (X) with some reagents namely, hydrazine hydrate, methyl amine, aniline, sodium thiophenolate, ethyl glycinate, thiosemicarbazide and thiourea, yielded pyridothieno-pyrimidine derivatives (XI-XVII) substituted at 4-position, respectively.