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144282-35-9

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144282-35-9 Usage

General Description

5-Azaspiro[2.4]heptan-7-amine, 5-(phenylmethyl)-, (S)-, also known as Vilazodone, is an antidepressant medication that is used to treat major depressive disorder in adults. It works by increasing the levels of serotonin, a neurotransmitter in the brain that helps regulate mood. Vilazodone is classified as a selective serotonin reuptake inhibitor and partial serotonin receptor agonist, meaning it helps to increase serotonin levels while also affecting serotonin receptors in the brain. It is available in tablet form and is typically taken orally once daily with food. Common side effects may include diarrhea, nausea, vomiting, and insomnia, and it should not be taken with MAO inhibitors or within 14 days of discontinuing an MAO inhibitor. Overall, 5-Azaspiro[2.4]heptan-7-amine, 5-(phenylmethyl)-, (S)- is an important medication for the treatment of major depressive disorder.

Check Digit Verification of cas no

The CAS Registry Mumber 144282-35-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,2,8 and 2 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 144282-35:
(8*1)+(7*4)+(6*4)+(5*2)+(4*8)+(3*2)+(2*3)+(1*5)=119
119 % 10 = 9
So 144282-35-9 is a valid CAS Registry Number.

144282-35-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (7S)-5-benzyl-5-azaspiro[2.4]heptan-7-amine

1.2 Other means of identification

Product number -
Other names (S)-7-Amino-5-benzyl-5-azaspiro[2.4]-heptane 2HCl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:144282-35-9 SDS

144282-35-9Relevant articles and documents

Preparation method of sitafloxacin hydrate

-

, (2019/02/04)

The invention discloses a preparation method of sitafloxacin hydrate. The method comprises the following steps: taking ethyl 4-bromoacetoacetate used as a raw material, enabling ethyl 4-bromoacetoacetate to be fully reacted with 1,2-dibromoethane and preparing the obtained product into a compound II in the presence of carbonyl reduction enzyme; taking the compound II, enabling the compound II to carry out cyclization reaction with benzylamine in a solvent in the presence of cesium carbonate, enabling the obtained product to be reacted with DPPA and preparing a compound IV; reducing nitrine group of the compound IV to prepare a compound V; connecting primary amine group of the compound V with a BOC protection group to obtain a compound VI; reducing the compound VI through Pd/C, enabling theobtained product to be reacted with 8-chlorine-6,7-difluoro-1-[(1R,2s)-2-fluorocyclopropyl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester to prepare a compound VIII; and carrying out deprotection of the compound VIII to obtain sitafloxacin hydrate. The sitafloxacin hydrate is few in preparation steps, simple in post-treatment and relatively high in yield.

Process for the preparation of optically active amines or salts thereof

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, (2008/06/13)

A process produces an optically active amine or its salt and includes the steps of reacting a ketone of Formula (1a) 1wherein R1 is typically an unsubstituted or substituted hydrocarbon group; and R2a is typically a hydrocarbon grou

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