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144409-99-4

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  • L-Aspartic acid,L-valyl-L-valylglycylglycyl-L-valyl-L-methionyl-L-leucylglycyl-L-isoleucyl-L-isoleucyl-L-alanylglycyl-L-lysyl-L-asparaginyl-L-serylglycyl-L-valyl-L-a-aspartyl-L-a-glutamyl-L-alanyl-L-p

    Cas No: 144409-99-4

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144409-99-4 Usage

General Description

Amyloid beta-protein (40-1) is a peptide that plays a critical role in the pathogenesis of Alzheimer's disease. It is a key component of amyloid plaques, which are a hallmark of the disease. The peptide is cleaved from a larger precursor protein and can form aggregates that are toxic to neurons. These aggregates can disrupt synaptic function and contribute to neuronal damage and death. Additionally, amyloid beta-protein (40-1) may also impair the clearance of amyloid beta from the brain, leading to further accumulation of the peptide. This accumulation is believed to contribute to the progressive cognitive decline seen in Alzheimer's disease. Therefore, understanding the mechanisms of amyloid beta-protein (40-1) aggregation and toxicity is crucial for developing potential treatments for this devastating neurodegenerative disease.

Check Digit Verification of cas no

The CAS Registry Mumber 144409-99-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,4,0 and 9 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 144409-99:
(8*1)+(7*4)+(6*4)+(5*4)+(4*0)+(3*9)+(2*9)+(1*9)=134
134 % 10 = 4
So 144409-99-4 is a valid CAS Registry Number.

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