144689-24-7 Usage
Description
Olmesartan, also known as Olmesartan medoxomil, is an angiotensin II receptor antagonist used in the treatment of hypertension. It belongs to a class of drugs called AT1 receptor blockers, which work by blocking the action of angiotensin II, a hormone responsible for narrowing blood vessels. This action results in lower blood pressure and reduced strain on the heart. Olmesartan is rapidly and completely bioactivated by ester hydrolysis during absorption from the gastrointestinal tract, and once converted to the active form, virtually no further metabolism occurs.
Uses
Used in Pharmaceutical Industry:
Olmesartan is used as an anti-hypertensive agent for the management of hypertension. It functions as an angiotensin II receptor antagonist, which helps in widening blood vessels and reducing blood pressure. The drug is also used in combination with other medications, such as the calcium channel blocker amlodipine, to enhance its effectiveness in treating high blood pressure. This combination product is sold under the tradename of Azor and was approved by the Food and Drug Administration (FDA) in September 2007.
Olmesartan is used as an angiotensin II (AT1) receptor antagonist for the treatment of hypertension. It is an effective medication that helps lower blood pressure by blocking the action of angiotensin II, a hormone that causes blood vessels to narrow. This results in reduced strain on the heart and improved cardiovascular health.
Biochem/physiol Actions
Olmesartan possesses anti-inflammatory and anti-oxidative stress properties. It protects neuronal cells against oligomerized amyloid β (Aβ)-induced cellular senescence.
Check Digit Verification of cas no
The CAS Registry Mumber 144689-24-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,6,8 and 9 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 144689-24:
(8*1)+(7*4)+(6*4)+(5*6)+(4*8)+(3*9)+(2*2)+(1*4)=157
157 % 10 = 7
So 144689-24-7 is a valid CAS Registry Number.