144830-15-9

• 

• Basic information

  1. Product Name: (-)-O-DESMETHYLTRAMADOL, HYDROCHLORIDE
  2. Synonyms: (-)-2-[(DIMETHYLAMINO)METHYL]-1-(3-HYDROXYPHENYL)CYCLOHEXANOL, HCL;(-)-(1S,2S)-O-DESMETHYL TRAMADOL HCL;(-)-O-DESMETHYLTRAMADOL, HYDROCHLORIDE;ODT;3-[(1S,2S)-2-[(diMethylaMino)Methyl]-1-hydroxycyclohexyl]phenol
  3. CAS NO:144830-15-9
  4. Molecular Formula: C15H24ClNO2
  5. Molecular Weight: 285.81
  6. EINECS: N/A
  7. Product Categories: Various Metabolites and Impurities;Metabolites
  8. Mol File: 144830-15-9.mol
  9. Article Data: 3

• Chemical Properties

  1. Melting Point: 141-142°C
  2. Boiling Point: 403.3±25.0 °C(Predicted)
  3. Flash Point: N/A
  4. Appearance: /
  5. Density: 1.104±0.06 g/cm3(Predicted)
  6. Refractive Index: N/A
  7. Storage Temp.: -20°C Freezer
  8. Solubility: N/A
  9. PKA: 10.00±0.10(Predicted)
  10. CAS DataBase Reference: (-)-O-DESMETHYLTRAMADOL, HYDROCHLORIDE(CAS DataBase Reference)
  11. NIST Chemistry Reference: (-)-O-DESMETHYLTRAMADOL, HYDROCHLORIDE(144830-15-9)
  12. EPA Substance Registry System: (-)-O-DESMETHYLTRAMADOL, HYDROCHLORIDE(144830-15-9)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 144830-15-9(Hazardous Substances Data)

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• Usage
• SDS
• Upstream product
• Downstream Products
• Article

144830-15-9 Suppliers

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• Phenol,3-[(1S,2S)-2-[(dimethylamino)methyl]-1-hydroxycyclohexyl]-

  Cas No: 144830-15-9

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• 10 Gram

• 500 Kilogram/Month

• Zibo Hangyu Biotechnology Development Co., Ltd
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• (-)-O-DESMETHYLTRAMADOL, HYDROCHLORIDE

  Cas No: 144830-15-9

• USD $ 2.0-2.0 / Kilogram

• 1 Kilogram

• 10000000 Kilogram/Year

• TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD
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• Phenol,3-[(1S,2S)-2-[(dimethylamino)methyl]-1-hydroxycyclohexyl]-

  Cas No: 144830-15-9

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• Antimex Chemical Limied
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• (-)-O-DESMETHYLTRAMADOL, HYDROCHLORIDE

  Cas No: 144830-15-9

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• BOC Sciences
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• (-)-O-DESMETHYLTRAMADOL,HCLCAS

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• Hangzhou Fandachem Co.,Ltd
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• (-)-O-DESMETHYLTRAMADOL, HYDROCHLORIDE

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• ZHEJIANG JIUZHOU CHEM CO.,LTD
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• (-)-O-DESMETHYLTRAMADOL,HYDROCHLORIDE

  Cas No: 144830-15-9

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• Finetech Industry Limited
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144830-15-9 Usage

Chemical Properties

White Crystalline Solid

Uses

A optically active metabolite of Tramadol.

Check Digit Verification of cas no

The CAS Registry Mumber 144830-15-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,8,3 and 0 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 144830-15:
(8*1)+(7*4)+(6*4)+(5*8)+(4*3)+(3*0)+(2*1)+(1*5)=119
119 % 10 = 9
So 144830-15-9 is a valid CAS Registry Number.

144830-15-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name	(-)-O-DESMETHYLTRAMADOL, HYDROCHLORIDE

1.2 Other means of identification

Product number	-
Other names	O-desmethyl-cis-tramadol

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:144830-15-9 SDS

144830-15-9Upstream product

• 36282-47-0 tramadol hydrochloride 
• 2914-77-4 tramadol 
• 27203-92-5 cis-tramadol 

144830-15-9Downstream Products

• 16412-54-7 (+/-)-mono-O-demethyltramadol hydrochloride 
• 144830-14-8 (+)-O-Demethyltramadol 
• 138853-75-5 3-<2-(e)-Dimethylaminomethyl-1(a)-hydroxycylohexyl>-phenyl-β-D-glucopyranuronsaeure 

144830-15-9Relevant articles and documents

A PROCESS FOR PREPARATION OF O-DESMETHYLTRAMADOL AND SALTS THEREOF

-

Page/Page column 11, (2019/04/11)

The present invention relates to a process of preparation of O-Desmethyl tramadol through potassium hydroxide mediated demethylation of Tramadol under phase transfer conditions.

COMPOSITIONS AND METHODS FOR OVERCOMING RESISTANCE TO TRAMADOL

-

Paragraph 0211, (2013/03/26)

There is disclosed a composition for oral administration of O-desmethyltramadol. There is further disclosed a method for treating disorders modulated by at least opiate receptor activity or monoamine activity, including acute and chronic pain, comprising administering a pharmaceutical formulation comprising O-desmethyltramadol. Compositions and methods are also provided that are effective for overcoming resistance to tramadol in patients.

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