146136-78-9 Usage
General Description
2,4-Diaminoquinoline is a chemical compound with the molecular formula C9H8N2. It is a yellow solid that is insoluble in water but soluble in organic solvents. 2,4-Diaminoquinoline is primarily used as a building block in the synthesis of pharmaceuticals, particularly antimalarial drugs. It has also been studied for its potential as a corrosion inhibitor in the oil and gas industry. Additionally, 2,4-Diaminoquinoline is known to exhibit antimicrobial and antifungal properties, making it a useful ingredient in certain industrial and agricultural applications. However, it is important to note that this compound can be toxic if ingested or inhaled, and proper precautions should be taken when handling it.
Check Digit Verification of cas no
The CAS Registry Mumber 146136-78-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,1,3 and 6 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 146136-78:
(8*1)+(7*4)+(6*6)+(5*1)+(4*3)+(3*6)+(2*7)+(1*8)=129
129 % 10 = 9
So 146136-78-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H9N3/c10-7-5-9(11)12-8-4-2-1-3-6(7)8/h1-5H,(H4,10,11,12)
146136-78-9Relevant articles and documents
Regioselective Azidation of 2,4-Dichloroquinolines
Steinschifter, Waltraud,Stadlbauer, Wolfgang
, p. 311 - 318 (2007/10/02)
Reactions of 2,4-dichloroquinolines (2a-f) with sodium azide in DMF lead either regioselectively to 4-azido-2-chloroquinolines (3a-f) or with excess of sodium azide and catalysts to 5-azido-tetrazoloquinolines (4a-f). 2,4-Dichloroquinolines (2g-i) having electron donating substituents in 3-position react with sodium azide in DMF to a mixture of 4-azido-2-chloroquinolines (3g-i) and 5-chlorotetrazoloquinolines (5g-i).When the reaction of the 2,4-dichloroquinolines (2a-i) with sodium azide is carried out in ethanol with addition of methanesulfonic acid, regioselectively 5-chloro-tetrazoloquinolines (5a-i) are obtained.Structural assignments of 3 and 5 have been carried out by 13C-NMR spectra, IR spectra and degradation reactions of the azido- and tetrazolo group to aminoquinolines (7 and 10) via iminophosphoranes (8 and 9).It could be shown that in 2-azido/tetrazolo-quinolines (4 and 5) the tetrazole ring structure is the dominant species.
