1462-73-3

• 

• Basic information

  1. Product Name: Dextroamphetamine hydrochloride
  2. Synonyms: Dextroamphetamine hydrochloride;(S)-Amphetamine Hydrochloride;(S)-1-Methyl-2-phenylethylaMine HCl;D-Amphetamine (hydrochloride) (exempt preparation)
  3. CAS NO:1462-73-3
  4. Molecular Formula: C₉H₁₃N*ClH
  5. Molecular Weight: 171.67
  6. EINECS: N/A
  7. Product Categories: Amines;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals
  8. Mol File: 1462-73-3.mol
  9. Article Data: 8

• Chemical Properties

  1. Melting Point: 151-153°C
  2. Boiling Point: 201.5 °C at 760 mmHg
  3. Flash Point: 87.4 °C
  4. Appearance: /
  5. Density: N/A
  6. Vapor Pressure: 0.307mmHg at 25°C
  7. Refractive Index: N/A
  8. Storage Temp.: Controlled Substance, -20°C Freezer
  9. Solubility: N/A
  10. CAS DataBase Reference: Dextroamphetamine hydrochloride(CAS DataBase Reference)
  11. NIST Chemistry Reference: Dextroamphetamine hydrochloride(1462-73-3)
  12. EPA Substance Registry System: Dextroamphetamine hydrochloride(1462-73-3)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 1462-73-3(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
• Downstream Products
• Article

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1462-73-3 Usage

Description

D-Amphetamine (hydrochloride) (exempt preparation) (Item No. 15650) is an analytical reference standard categorized as an amphetamine. Amphetamine is a psychotropic compound that is abused recreationally. Amphetamine is regulated as a Schedule II compound in the United States. D-Amphetamine (hydrochloride) (exempt preparation) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

Chemical Properties

White Solid

Uses

CNS stimulant; anorexic. More active isomer of Amphetamine. Induces release of catecholamines and serotonin by displacing the monoamines from their vesicular storage sites; blocks catecholamine reuptake. Controlled substance (stimulant).

Check Digit Verification of cas no

The CAS Registry Mumber 1462-73-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,6 and 2 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1462-73:
(6*1)+(5*4)+(4*6)+(3*2)+(2*7)+(1*3)=73
73 % 10 = 3
So 1462-73-3 is a valid CAS Registry Number.

InChI:InChI=1/C9H13N.ClH/c1-8(10)7-9-5-3-2-4-6-9;/h2-6,8H,7,10H2,1H3;1H/t8-;/m0./s1

1462-73-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	(S)-Amphetamine Hydrochloride

1.2 Other means of identification

Product number	-
Other names	(+)-Amphetamine hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1462-73-3 SDS

1462-73-3Upstream product

• 492-41-1 (1R,2S)-norephedrine 
• 104-54-1 3-Phenylpropenol 
• 3198-15-0 (1R,2S)-(-)-norephedrine hydrochloride 
• 51-64-9 dexamfetamine 
• 79219-15-1 (S)-2-<(ethoxycarbonyl)amino>-1-phenyl-1-propanone 
• 293305-69-8 (R)-2-(N-t-butoxycarbonylamino)-3-phenyl-1-iodopropane 
• 106454-69-7 N-tert-butoxycarbonyl-D-Phenylalaninol 
• 673-06-3 D-(R)-phenylalanine 
• 5267-64-1 (R)-2-amino-3-phenylpropanol 
• 14593-16-9 N-acetylamphetamine 
• 293305-71-2 tert-butyl (1S)-1-methyl-2-phenylethyl carbamate 
• 75-16-1 methylmagnesium bromide 
• 221375-48-0 (N(E),R)-2-methyl-N-(2-phenylethylidene)-2-propanesulfinamide 
• 87923-38-4 (S,S)-(-)-N-(1-phenylethyl)-1-phenyl-2-aminopropane hydrochloride 

1462-73-3Downstream Products

• 92644-85-4 Laevulinoyl-(+)-amphetamin 
• 15547-39-4 N-<(S)-1-methyl-2-phenylethyl>formamide 
• 92321-55-6 Isopentanoyl-(+)-amphetamin 
• 92322-28-6 Pentanoyl-(+)-amphetamin 

1462-73-3Relevant articles and documents

A short enantioselective synthesis of ephedrine, amphetamine and their analogues via two stereocentered Co(III)-catalyzed hydrolytic kinetic resolution of racemic syn-benzyloxy epoxide

Lalwani, Komal G.,Sudalai, Arumugam

, p. 6488 - 6490 (2015/11/16)

An efficient route for the synthesis of 6 drugs belonging to phenethylamine and amphetamine classes in excellent overall yields and high optical purity has been described. The strategy involves introduction of stereogenic centers by means of two-stereocentered Co(III)-catalyzed hydrolytic kinetic resolution (HKR) of racemic syn-benzyloxy epoxide followed by Pd-catalyzed regioselective cationic hydrogenation of amino alcohols as the key reactions.

Resolution of chiral aliphatic and arylalkyl amines using immobilized Candida antarctica lipase and isolation of their R- and S-enantiomers

Davis,Durden

, p. 569 - 578 (2007/10/03)

The resolution of chiral aliphatic and arylalkyl amines in high enantiomeric excess (up to 97.5% ee for the R-enantiomers and up to 99.9% ee for the S-enantiomers) and good yield (50-80%) using immobilized Candida antarctica lipase and ethyl acetate as acyl donor has been demonstrated. A second resolution on the Ramine increased the enantiomeric excess to more than 99.5% (up to 99.9%).

Asymmetric synthesis of chiral amines by highly diastereoselective 1,2- additions of organometallic reagents to N-tert-butanesulfinyl imines

Cogan, Derek A.,Liu, Guangcheng,Ellman, Jonathan

, p. 8883 - 8904 (2007/10/03)

High yielding and highly diastereoselective methods for 1,2-additions of organometallic reagents to N-tert-butanesulfinyl aldimines (2) and N-tert- butanesulfinyl kerimines (3) are described. The additions of alkyl, aryl, alkenyl, and allyl carbanions to a diverse set of imines with different steric and electronic properties are demonstrated. Acidic methanolysis of the sulfinamide products (4 and 6) delivers highly enantioenriched α-branched and α,α-dibranched amines. Since a broad range of sulfinyl imines are easily accessible from aldehydes and ketones, a wide variety of enantioentriched amines may be prepared.