146235-33-8

• 

• Basic information

  1. Product Name: 2-Oxazolidinone, 3-[(2E)-1-oxo-3-phenyl-2-propenyl]-4-phenyl-, (4S)-
  2. Synonyms: 2-Oxazolidinone,3-[(2E)-1-oxo-3-phenyl-2-propenyl]-4-phenyl-,(4S);
  3. CAS NO:146235-33-8
  4. Molecular Formula: C18H15NO3
  5. Molecular Weight: 293.322
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 146235-33-8.mol
  9. Article Data: 15

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: N/A
  5. Density: N/A
  6. Refractive Index: N/A
  7. Storage Temp.: N/A
  8. Solubility: N/A
  9. CAS DataBase Reference: 2-Oxazolidinone, 3-[(2E)-1-oxo-3-phenyl-2-propenyl]-4-phenyl-, (4S)-(CAS DataBase Reference)
  10. NIST Chemistry Reference: 2-Oxazolidinone, 3-[(2E)-1-oxo-3-phenyl-2-propenyl]-4-phenyl-, (4S)-(146235-33-8)
  11. EPA Substance Registry System: 2-Oxazolidinone, 3-[(2E)-1-oxo-3-phenyl-2-propenyl]-4-phenyl-, (4S)-(146235-33-8)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 146235-33-8(Hazardous Substances Data)

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• Downstream Products
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• 2-Oxazolidinone, 3-[(2E)-1-oxo-3-phenyl-2-propenyl]-4-phenyl-, (4S)-

  Cas No: 146235-33-8

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• 2-Oxazolidinone, 3-[(2E)-1-oxo-3-phenyl-2-propenyl]-4-phenyl-, (4S)-

  Cas No: 146235-33-8

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146235-33-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 146235-33-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,2,3 and 5 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 146235-33:
(8*1)+(7*4)+(6*6)+(5*2)+(4*3)+(3*5)+(2*3)+(1*3)=118
118 % 10 = 8
So 146235-33-8 is a valid CAS Registry Number.

146235-33-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	(4S)-4-phenyl-3-(3-phenylprop-2-enoyl)-1,3-oxazolidin-2-one

1.2 Other means of identification

Product number	-
Other names	2-Oxazolidinone,3-[(2E)-1-oxo-3-phenyl-2-propenyl]-4-phenyl-,(4S)

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:146235-33-8 SDS

146235-33-8Upstream product

• 140-10-3 (E)-3-phenylacrylic acid 
• 621-82-9 Cinnamic acid 
• 102-92-1 cinnamoyl chloride 
• 90319-52-1 (4R)-phenyl-2-oxazolidinone 
• 102-92-1 Cinnamoyl chloride 
• 99395-88-7 (S)-4-phenyl-2-oxazolidinone 
• 20989-17-7 (2S)-2-phenylglycinol 
• 2935-35-5 (S)-2-phenylglycine 

146235-33-8Downstream Products

• 349547-18-8 (S)-6-methyl-4-phenylchroman-2-one 
• 215929-27-4 (R)-3-[(R)-3-(2-benzyloxy-5-methylphenyl)-3-phenylpropionyl]-4-phenyloxazolidin-2-one 
• 1191280-59-7 (R)-3-((R)-3-(2-(benzyloxy)-5-(benzyloxymethyl)phenyl)-3-phenylpropanoyl)-4-phenyloxazolidin-2-one 
• 1191280-66-6 (R)-3-((R)-3-(2-(benzyloxy)-5-(benzyloxy(methyl-d2))phenyl)-3-phenylpropanoyl)-4-phenyloxazolidin-2-one 
• 1191280-49-5 (R)-3-((R)-3-(2-(benzyloxy)-5-(methyl-d3)phenyl)-3-phenylpropanoyl)-4-phenyloxazolidin-2-one 
• 160538-63-6 (4R)-4-phenyl-3-<(3R)-3-phenylbutyryl>oxazolidin-2-one 
• 1414566-89-4 (R)-3-((3S,4R)-1-(2-methoxyethyl)-4-phenylpyrrolidine-3-carbonyl)-4-phenyloxazolidin-2-one 
• 1414566-96-3 benzyl (3S,4R)-1-(2-methoxyethyl)-4-phenylpyrrolidin-3-ylcarbamate 
• 1414566-94-1 (3S,4R)-1-(2-methoxyethyl)-4-phenylpyrrolidine-3-carboxylic acid 
• 1458609-46-5 4-methoxybenzyl (R)-(2-phenylpent-4-en-1-yl)carbamate 

146235-33-8Relevant articles and documents

DIALKYLAMINOARYLCYCLOALKYLAMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN

-

, (2021/08/05)

The present invention relates to compounds of formula (I), where the variables are as defined in the claims, that show pharmacological activity towards the subunit α2δ of voltage-gated calcium channels (VGCC), especially the α2δ-1 subunit of voltage-gated calcium channels or dual activity towards the subunit α2δ of voltage-gated calcium channels (VGCC), especially the α2δ-1 subunit of voltage-gated calcium channels, and the μ-opioid receptor (MOR or mu-opioid). The invention also relates to a process for the preparation of said compounds as well as to compositions comprising them, and to their use as medicaments, particularly in the treatment of pain and pain-related conditions.

Conjugate addition of aryl nucleophiles to α,β-unsaturated cinnamic acid derivatives containing Evans type chiral auxiliaries

Leitis, Zigmārs,Lūsis, Viesturs

, p. 843 - 851 (2016/09/02)

Cinnamides containing oxazolidin-2-one type auxiliaries have been prepared. A novel pathway to chiral 4-aryl-6-methyl-3,4-dihydrocoumrines via the asymmetric conjugate addition of arylmagnesium bromides to these cinnamides is described.

PYRROLIDINYL UREA, THIOUREA, GUANIDINE AND CYANOGUANIDINE COMPOUNDS AS TRKA KINASE INHIBITORS

-

Paragraph 00349, (2014/06/11)

Compounds of Formula I: or stereoisomers, tautomers, or pharmaceutically acceptable salts, or solvates or prodrugs thereof, where R1, R2, Ra, Rb, Rc, Rd, X, Ring B, and Ring C are as defined herein, and wherein Ring B moiety and the NH-C(=X)-NH moiety are in the trans configuration, are inhibitors of TrkA kinase and are useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation/inflammatory diseases, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis and pelvic pain syndrome.

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