146253-26-1Relevant articles and documents
Total Syntheses of Ellipticine Alkaloids and their Amino Analogues
Sha, Chin-Kang,Yang, Jeng-Fenn
, p. 10645 - 10654 (2007/10/02)
Staudinger reaction of 9 with triphenylphosphine gave 2,4-dihydropyrroloindole 10.Treatment of 10 with di-tert-butyl dicarbonate and 4-dimethylaminopyridine gave 11.Diels-Alder reaction of 11 with 3,4-pyridyne gave cycloadducts 12 and 13, which were converted into ellipticine 1 and isoellipticine 2.New amino analogues of ellipticine 27 and 28 were also synthesized by this new route.Key words: Ellipticine, 2,4-Dihydropyrroloindole, Staudinger Reaction