146377-62-0Relevant articles and documents
Tailoring the Reactivity of the Langlois Reagent and Styrenes with Cyanoarenes Organophotocatalysts under Visible-Light
Louvel, Dan,Souibgui, Amel,Taponard, Alexis,Rouillon, Jean,ben Mosbah, Mongi,Moussaoui, Younes,Pilet, Guillaume,Khrouz, Lhoussain,Monnereau, Cyrille,Vantourout, Julien C.,Tlili, Anis
supporting information, p. 139 - 148 (2021/10/25)
The selective one-step access to fluoroalkylated hexestrol derivatives, nonsteroidal estrogens, is achieved in good to excellent isolated yields under organophotoredox conditions by using the stable and easy to handle Langlois reagent. Furthermore, the ch
Copper-Catalyzed Decarboxylative Difluoromethylation
Zeng, Xiaojun,Yan, Wenhao,Zacate, Samson B.,Chao, Tzu-Hsuan,Sun, Xiaodong,Cao, Zhi,Bradford, Kate G. E.,Paeth, Matthew,Tyndall, Sam B.,Yang, Kundi,Kuo, Tung-Chun,Cheng, Mu-Jeng,Liu, Wei
supporting information, p. 11398 - 11403 (2019/08/20)
We report herein a highly efficient Cu-catalyzed protocol for the conversion of aliphatic carboxylic acids to the corresponding difluoromethylated analogues. This robust, operationally simple and scalable protocol tolerates a variety of functional groups and can convert a diverse array of acid-containing complex molecules to the alkyl-CF2H products. Mechanistic studies support the involvement of alkyl radicals.
Aminodifluorosulfinium Tetrafluoroborate salts as stable and crystalline deoxofluorinating reagents
Beaulieu, Francis,Beauregard, Louis-Philippe,Courchesne, Gabriel,Couturier, Michel,Laflamme, Francois,L'Heureux, Alexandre
supporting information; experimental part, p. 5050 - 5053 (2009/12/28)
Aminodifluorosulfinium tetrafluoroborate salts were found to act as efficient deoxofluorinating reagents when promoted by an exogenous fluoride source and, In most cases, exhibited greater selectivity by providing less elimination byproduct as compared to DAST and DeoxoFluor. Aminodifluorosulfinium tetrafluoroborates are easy handled crystalline salts that show enhanced thermal stability over dialkylaminosulfur trifluorides, are storage-stable, and unlike DAST and Deoxo-Fluor do not react violently with water.
