147152-22-5 Usage
Description
(+)-Hydroxyzine is a medication primarily used to treat anxiety and tension by blocking the effects of histamine, a natural substance in the body involved in allergic reactions. This action helps alleviate symptoms such as itching, hives, and sneezing. It also serves as a sedative for anxiety and tension and can be prescribed to manage nausea and vomiting.
Used in Pharmaceutical Industry:
(+)-Hydroxyzine is used as an anxiolytic and antihistamine medication for treating anxiety, tension, and allergic symptoms such as itching and hives. It is also utilized as a sedative to help manage nausea and vomiting. This medication is available in oral and injectable formulations and should be used with caution in patients with specific medical conditions, such as glaucoma, urinary retention, or heart disease. Additionally, due to its potential to cause drowsiness, it is advised to exercise caution when driving or operating heavy machinery.
Check Digit Verification of cas no
The CAS Registry Mumber 147152-22-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,1,5 and 2 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 147152-22:
(8*1)+(7*4)+(6*7)+(5*1)+(4*5)+(3*2)+(2*2)+(1*2)=115
115 % 10 = 5
So 147152-22-5 is a valid CAS Registry Number.
147152-22-5Relevant articles and documents
Iridium/graphene nanostructured catalyst for the: N -alkylation of amines to synthesize nitrogen-containing derivatives and heterocyclic compounds in a green process
Chen, Tsun-Ren,Chen, Yi-Sheng,Chen, Yu-Tung,Lee, Wen-Jen,Lin, Yen-Hsing,Wang, Hao-Chen
, p. 4760 - 4770 (2022/02/21)
A facile iridium/graphene-catalyzed methodology providing an efficient synthetic route for C-N bond formation is reported. This catalyst can directly promote the formation of C-N bonds, without pre-activation steps, and without solvents, alkalis and other additives. This protocol provides a direct N-alkylation of amines using a variety of primary and secondary alcohols with good selectivity and excellent yields. Charmingly, the use of diols resulted in intermolecular cyclization of amines, and such products are privileged structures in biologically active compounds. Two examples illustrate the advantages of this catalyst in organic synthesis: the tandem catalysis to synthesize hydroxyzine, and the intermolecular cyclization to synthesize cyclizine. Water is the only by-product, which makes this catalytic process sustainable and environmentally friendly. This journal is
