147201-04-5

• 

• Basic information

  1. Product Name: 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
  2. Synonyms: 2’-TBDMS-rG(N-ibu)Phosphoramidite;5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite;5'-O-DMT-2'-TBDMS-rG(N-iBu)-3'-CEDPA;(2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(tert-butyldimethylsilyloxy)-5-(2-isobutyramido-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3-yl 2-cyanoethyl diisopropylphosphoramidite;REF DUPL: 2'-TBDMS-rG(N-ibu)Phosphoramidite;i-bu-rG Phosphoramidite;DMT-2′O-TBDMS-rG(ib) Phosphoramidite;2'-TBDMS-ibu-G-CE-Phosphoramidite
  3. CAS NO:147201-04-5
  4. Molecular Formula: C₅₀H₆₈N₇O₉PSi
  5. Molecular Weight: 970.187
  6. EINECS: 2017-001-1
  7. Product Categories: N/A
  8. Mol File: 147201-04-5.mol
  9. Article Data: 6

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: white to off-white/
  5. Density: N/A
  6. Refractive Index: N/A
  7. Storage Temp.: ?20°C
  8. Solubility: N/A
  9. PKA: 9.16±0.20(Predicted)
  10. CAS DataBase Reference: 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite(CAS DataBase Reference)
  11. NIST Chemistry Reference: 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite(147201-04-5)
  12. EPA Substance Registry System: 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite(147201-04-5)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany: 3
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 147201-04-5(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
• Downstream Products
• Article

147201-04-5 Suppliers

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• ibu-rG Phosphoramidite

  Cas No: 147201-04-5

• No Data

• 100 Gram

• 100 Metric Ton/Year

• Wuhu Nuowei Chemistry Technologies Co., Ltd.
• Contact Supplier

• (2R,3R,4R,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-4-((TERT-BUTYLDIMETHYLSILYL)OXY)-5-(2-ISOBUTYRAMIDO-6-OXO-1H-PURIN-9(6H)-YL)TETRAHYDROFURAN-3-YL (2-CYANOETHYL) DIISOPROPYLPHOSPHORAMIDITE

  Cas No: 147201-04-5

• USD $ 3.0-3.0 / Kilogram

• 1 Kilogram

• 1-100 Metric Ton/Month

• Dayang Chem (Hangzhou) Co.,Ltd.
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• High quality I-Bu-Rg Phosphoramidite supplier in China

  Cas No: 147201-04-5

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• 1 Kilogram

• 30 Metric Ton/Month

• Simagchem Corporation
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• Factory Supply I-Bu-Rg Phosphoramidite

  Cas No: 147201-04-5

• No Data

• 1

• 1

• Ality Chemical Corporation
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• 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

  Cas No: 147201-04-5

• USD $ 9.0-99.0 / Kilogram

• 1 Kilogram

• 1 Kilogram/Month

• Hebei Nengqian Chemical Import and Export Co., LTD
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• Top Purity CAS 147201-04-5 with fast shipping

  Cas No: 147201-04-5

• USD $ 139.0-210.0 / Kilogram

• 1 Kilogram

• 1000 Kilogram/Day

• Zhuozhou Wenxi import and Export Co., Ltd
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• N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-guanosine-3'-cyanoethylPhosphoramidite

  Cas No: 147201-04-5

• No Data

• 1 Milligram

• Kilogram/Month

• NewCan Biotech Limited
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• ibu-rG Phosphoramidite

  Cas No: 147201-04-5

• No Data

• 4 Kilogram

• Metric Ton/Day

• SHANGHAI T&W PHARMACEUTICAL CO., LTD.
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• Guanosine,5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)-,3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)

  Cas No: 147201-04-5

• No Data

• 10 Gram

• 500 Kilogram/Month

• Zibo Hangyu Biotechnology Development Co., Ltd
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• DMT-2'-O-TBDMS-G(iBu)-CE Phosphoramidite

  Cas No: 147201-04-5

• No Data

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• YUNBIO TECH CO.,LTD
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147201-04-5 Usage

Uses

Different sources of media describe the Uses of 147201-04-5 differently. You can refer to the following data:
1. 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is mainly used as a biochemical reagent.
2. DMT-2′O-TBDMS-rG(ib) Phosphoramidite was used to develop receptor-like approaches for high fidelity base paring at the 3’-terminus.

Check Digit Verification of cas no

The CAS Registry Mumber 147201-04-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,2,0 and 1 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 147201-04:
(8*1)+(7*4)+(6*7)+(5*2)+(4*0)+(3*1)+(2*0)+(1*4)=95
95 % 10 = 5
So 147201-04-5 is a valid CAS Registry Number.

147201-04-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	DMT-2'O-TBDMS-rG(ib) Phosphoramidite

1.2 Other means of identification

Product number	-
Other names	CEPA-rG

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:147201-04-5 SDS

147201-04-5Upstream product

• 102691-36-1 N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite 
• 81279-39-2 N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide 
• 124482-92-4 2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 
• 108-18-9 diisopropylamine 

147201-04-5Downstream Products

• 1220703-64-9 5'-O-DMTr-rG(iBu)p(CNE)-rA(Bz)po(CNE)dT-3'-O-Lev 

147201-04-5Relevant articles and documents

Microwave-assisted preparation of nucleoside-phosphoramidites

Meher,Efthymiou,Stoop,Krishnamurthy

supporting information, p. 7463 - 7465 (2014/07/07)

Microwave-assisted phosphitylation of sterically hindered nucleosides is demonstrated to be an efficient method for the preparation of corresponding phosphoramidites (otherwise onerous under standard conditions) and is shown to be general in its applicability. the Partner Organisations 2014.

c-di-GMP displays A monovalent metal ion-dependent polymorphism

Zhang, Zhaoying,Gaffney, Barbara L.,Jones, Roger A.

, p. 16700 - 16701 (2007/10/03)

Cyclic diguanosine monophosphate (c-di-GMP) is known to be an important signaling molecule that regulates the formation of bacterial biofilms. We demonstrate here by UV, CD, and NMR that it displays a surprising polymorphism that varies with the monovalen

Methods for synthesizing nucleosides, nucleoside derivatives and non-nucleoside derivatives

-

, (2008/06/13)

The present invention provides methods for the chemical synthesis of nucleosides and derivatives thereof, including 2′-amino, 2′-N-phthaloyl, 2′-O-methyl, 2′-O-silyl, 2′OH nucleosides, C-nucleosides, nucleoside phosphoramidites, C-nucleoside phosphoramidites, and non-nucleoside derivatives.

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