14903-93-6Relevant articles and documents
One pot synthesis of micromolar BACE-1 inhibitors based on the Dihydropyrimidinone scaffold and their Thia and Imino analogues
Bais, Jessica,Benedetti, Fabio,Berti, Federico,Cerminara, Iole,Drioli, Sara,Felluga, Fulvia,Funicello, Maria,Regini, Giorgia,Vidali, Mattia
, (2020/09/18)
A library of dihydropyrimidinones was synthesized via a “one-pot” three component Biginelli reaction using different aldehydes in combination with β-dicarbonyl compounds and urea. Selected 2-thiooxo and 2-imino analogs were also obtained with the Biginell