149092-50-2 Usage
Uses
Different sources of media describe the Uses of 149092-50-2 differently. You can refer to the following data:
1. A selective ErbB2 inhibitor
2. AG 825 is a selective ErbB2 (Neu) inhibitor and apoptosis inducer.
Definition
ChEBI: An organic sulfide that consists of 1,3-benzothiazole-2-thiol in which the hydrogen attached to the sulfur atom is replaced by a 5-[(1E)-3-amino-2-cyano-3-oxoprop-1-en-1-yl]-2-hydroxy-3-methoxybenzyl group. It acts as an epidermal growth
factor receptor antagonist.
Biological Activity
Selective ErbB2 inhibitor (IC 50 values are 0.15 and 19 mM at ErbB2 and ErbB1 respectively). Preferentially triggers p38 MAP kinase-dependent apoptosis in androgen-independent prostate cancer cells.
Check Digit Verification of cas no
The CAS Registry Mumber 149092-50-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,0,9 and 2 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 149092-50:
(8*1)+(7*4)+(6*9)+(5*0)+(4*9)+(3*2)+(2*5)+(1*0)=142
142 % 10 = 2
So 149092-50-2 is a valid CAS Registry Number.
InChI:InChI=1/C19H15N3O3S2/c1-25-15-8-11(6-12(9-20)18(21)24)7-13(17(15)23)10-26-19-22-14-4-2-3-5-16(14)27-19/h2-8,23H,10H2,1H3,(H2,21,24)/b12-6+
