14944-23-1Relevant articles and documents
Lewis Acid Promoted Dearomatization of Naphthols
Boldrini, Cosimo,Casti?eira Reis, Marta,Harutyunyan, Syuzanna R.,Kulish, Kirill,Pérez, Juana M.
, p. 15843 - 15846 (2020)
Two-step dearomative functionalization of naphthols promoted by Lewis acids and copper(I) catalysis was developed. Initially, Lewis acid complexation inverted the electronic properties of the ring and established an equilibrium with the dearomatized counterpart. Subsequent trapping of the dearomatized intermediate with organometallics as well as organophosphines was demonstrated and provided the corresponding dearomatized products.
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Bachmann,Struve
, p. 1618 (1940)
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NAPHT- 2 -YLACETIC ACID DERIVATIVES TO TREAT AIDS
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Page/Page column 328, (2012/01/15)
The invention provides compounds of formula (I): or a salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula I and therapeutic methods for treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS or ARC symptoms in a mammal using compounds of formula (I).