15066-28-1Relevant articles and documents
Probing the mechanism of Baylis-Hillman reaction in ionic liquids
Singh, Anshu,Kumar, Anil
, p. 8775 - 8779,5 (2012)
The kinetic data for a Baylis-Hillman reaction in certain ionic liquids possessing ethylsulfate anion [EtSO4]- demonstrate that the rate determining step (RDS) is second order in aldehyde, but first order in acrylate and DABCO. This observation is similar to the one made by McQuade et al., who carried out this reaction in an aprotic polar solvent like DMSO. However, this is in contrast to the general observation that RDS is first order in aldehyde, acrylate, and DABCO in organic solvents.
Bringing a Molecular plus One: Synergistic Binding Creates Guest-Mediated Three-Component Complexes
Beyeh, Ngong Kodiah,Dashti, Mohadeseh,Lahtinen, Manu,Pan, Fangfang,Puttreddy, Rakesh,Rissanen, Kari,Taimoory, S. Maryamdokht,Trant, John F.,Twum, Kwaku
, p. 5884 - 5894 (2020/05/20)
Cethyl-2-methylresorcinarene (A), pyridine (B), and a set of 10 carboxylic acids (Cn) associate to form A·B·Cn ternary assemblies with 1:1:1 stoichiometry, representing a useful class of ternary systems where the guest mediates complex formation between the host and a third component. Although individually weak in solution, the combined strength of the multiple noncovalent interactions organizes the complexes even in a highly hydrogen-bond competing methanol solution, as explored by both experimental and computational methods. The interactions between A·B and Cn are dependent on the pKa values of carboxylic acids. The weak interactions between A and C further reinforce the interactions between A and B, demonstrating positive cooperativity. Our results reveal that the two-component system such as that formed by A and B can form the basis for the development of specific sensors for the molecular recognition of carboxylic acids.
