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151055-86-6

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151055-86-6 Usage

General Description

2-Imidazol-1-yl-benzaldehyde is a chemical compound with a molecular formula C10H8N2O. It is a pale yellow solid that is primarily used as a building block for the synthesis of various pharmaceutical compounds, especially those in the field of antihistamines and other medications that act on the central nervous system. It is also used in the production of dyes and fine chemicals. 2-Imidazol-1-yl-benzaldehyde is known for its mild and pleasant odor and is considered to be relatively stable under normal conditions. Its chemical structure features both an imidazole and an aldehyde group, giving it unique reactivity and properties that make it useful in a variety of synthetic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 151055-86-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,0,5 and 5 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 151055-86:
(8*1)+(7*5)+(6*1)+(5*0)+(4*5)+(3*5)+(2*8)+(1*6)=106
106 % 10 = 6
So 151055-86-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H8N2O/c13-7-9-3-1-2-4-10(9)12-6-5-11-8-12/h1-8H

151055-86-6Relevant articles and documents

Transition-metal-free insertion of benzyl bromides into 2-(1H-benzo[d]imidazol-1-yl)benzaldehyde: One-pot switchable syntheses of benzo[4,5]imidazo[1,2-a]quinolin-5(7H)-ones and 3-arylquinolin-4-ones mediated by base

Xu, Huayan,Xu, Liang,Luo, Xiaowei,Wang, Junfeng,Zhou, Xuefeng,Yang, Bin,Li, Ding,Luo, Zaigang,Liu, Yonghong,Liao, Shengrong

, p. 2785 - 2796 (2019/04/13)

A transition-metal-free insertion of benzyl group between aldehyde and imidazole of 2-(1H-benzo[d]imidazol-1-yl)benzaldehyde was achieved for the first time. Two diverse sets of quinolin-4-one derivatives: benzo[4,5]imidazo[1,2-a]quinolin-5(7H)-ones (2) and 3-arylquinolin-4-ones (3) were synthesized based on identical starting materials 2-(1H-benzo[d]imidazol-1-yl)benzaldehydes (1) and benzyl bromides. In the preparations, two key intermediates I and II were involved and might be synthesized in situ through the reaction of an intra-Breslow intermediate with benzyl bromide via an enol attack in the presence of base or a NHC-based enamine attack in the absence of base, respectively, in which the intra-Breslow intermediate might function as a nucleophilic reagent by following two novel different pathways.

Magnetically retrievable lepidocrocite supported copper oxide nanocatalyst (Fe-CuO) for N-arylation of imidazole

Sivakami,Babu, S. Ganesh,Dhanuskodi,Karvembu

, p. 8571 - 8578 (2015/03/03)

A simple and efficient lepidocrocite-supported copper oxide catalyst (Fe-CuO) has been successfully prepared by a simple precipitation method in aqueous medium from readily available inexpensive starting materials and was used as a heterogeneous nanocatal

Silver(I)-promoted intramolecular addition of N-heterocyclic carbenes towards unsaturated esters in water

Shang, Xiaobo,Chen, Chao,Qiu, Huayu,Chen, Wanzhi

, p. 3073 - 3077 (2014/04/17)

Silver(I)-promoted intramolecular addition reaction between N-heterocyclic carbene and unsaturated esters in water is described. The reaction leads to 1H-imidazo[1,2-a]indole derivatives in moderate to excellent yields.

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