151070-87-0Relevant articles and documents
Novel histamine H3 receptor antagonists based on the 4-[(1H-imidazol-4-yl)methyl]piperidine scaffold
Vaccaro, Wayne D.,Sher, Rosy,Berlin, Michael,Shih, Neng-Yang,Aslanian, Robert,Schwerdt, John H.,McCormick, Kevin D.,Piwinski, John J.,West Jr., Robert E.,Anthes, John C.,Williams, Shirley M.,Wu, Ren-Long,She, H. Susan,Rivelli, Maria A.,Mutter, Jennifer C.,Corboz, Michel R.,Hey, John A.,Favreau, Leonard
, p. 395 - 399 (2007/10/03)
We report the discovery of novel histamine H3 receptor antagonists based on 4-[(1H-imidazol-4-yl)methyl]piperidine. The most potent compounds in the series (e.g., 7) result from the attachment of a substituted aniline amide to the main pharmaco