1511-16-6

• 

• Basic information

  1. Product Name: 4-[4-(4-CHLOROPHENYL)-4-HYDROXY-1-PIPERIDINYL]-1-(4-FLUOROPHENYL)-1-BUTANONE HYDROCHLORIDE
  2. Synonyms: 4-[4-(4-CHLOROPHENYL)-4-HYDROXY-1-PIPERIDINYL]-1-(4-FLUOROPHENYL)-1-BUTANONE HYDROCHLORIDE;HALOPERIDOL HYDROCHLORIDE
  3. CAS NO:1511-16-6
  4. Molecular Formula: C₂₁H₂₃ClFNO₂*ClH
  5. Molecular Weight: 412.33
  6. EINECS: N/A
  7. Product Categories: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
  8. Mol File: 1511-16-6.mol
  9. Article Data: 1

• Chemical Properties

  1. Melting Point: 226-227.5°
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: /
  5. Density: N/A
  6. Refractive Index: N/A
  7. Storage Temp.: N/A
  8. Solubility: insoluble in H2O; ≥10.31 mg/mL in DMSO; ≥2.96 mg/mL in EtOH with gentle warming and ultrasonic
  9. CAS DataBase Reference: 4-[4-(4-CHLOROPHENYL)-4-HYDROXY-1-PIPERIDINYL]-1-(4-FLUOROPHENYL)-1-BUTANONE HYDROCHLORIDE(CAS DataBase Reference)
  10. NIST Chemistry Reference: 4-[4-(4-CHLOROPHENYL)-4-HYDROXY-1-PIPERIDINYL]-1-(4-FLUOROPHENYL)-1-BUTANONE HYDROCHLORIDE(1511-16-6)
  11. EPA Substance Registry System: 4-[4-(4-CHLOROPHENYL)-4-HYDROXY-1-PIPERIDINYL]-1-(4-FLUOROPHENYL)-1-BUTANONE HYDROCHLORIDE(1511-16-6)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 1511-16-6(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
• Downstream Products
• Article

1511-16-6 Suppliers

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• Factory Supply 1-Butanone,4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-,hydrochloride

  Cas No: 1511-16-6

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• Ality Chemical Corporation
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• 1-Butanone, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-, hydrochloride

  Cas No: 1511-16-6

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• SAGECHEM LIMITED
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• 4-[4-(4-CHLOROPHENYL)-4-HYDROXY-1-PIPERIDINYL]-1-(4-FLUOROPHENYL)-1-BUTANONE HYDROCHLORIDE

  Cas No: 1511-16-6

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• ZHEJIANG JIUZHOU CHEM CO.,LTD
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• Haloperidol hydrochloride

  Cas No: 1511-16-6

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• 1 Gram

• 10 Metric Ton/Month

• Changzhou Extraordinary Pharmatech co.,LTD
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• 4-[4-(4-CHLOROPHENYL)-4-HYDROXY-1-PIPERIDINYL]-1-(4-FLUOROPHENYL)-1-BUTANONE HYDROCHLORIDE

  Cas No: 1511-16-6

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• Wuxi Morality Chemical Co., Ltd
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1511-16-6 Usage

Uses

Haloperidol Hydrochloride is the salt analogue of Haloperidol (H103700) a dopamine inverse agonist, antidyskinetic and antipsychotic agent.

Biological Activity

haloperidol hydrochloride is an antipsychotic drug that has similar actions to the antipsychotic medicine phenothiazine [1].haloperidol hydrochloride has been reported to play a role as an inverse agonist of dopamine. in addition, haloperidol hydrochloride has been found to be highlt potent neuroleptic by relieving nervous through the depression of nerve function. besides, haloperidol hydrochloride has shown about 50-fold potency than chiorpromazine, the other antipsychotic drug. haloperidol hydrochloride has shown beneficial effects in the treatment of delusions and hallucinations. these effects are mainly achieved through blockage of dopamine receptors in the mesocortex and limbic system. haloperidol hydrochloride has been revealed to prevent the effects of dopamine in the nigrostriatal pathways, which probably explains the associated side effects such as akathisia and dystonias[1].

references

[1] dr ananya mandal, md .haloperidol pharmacology.

Check Digit Verification of cas no

The CAS Registry Mumber 1511-16-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,1 and 1 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1511-16:
(6*1)+(5*5)+(4*1)+(3*1)+(2*1)+(1*6)=46
46 % 10 = 6
So 1511-16-6 is a valid CAS Registry Number.

1511-16-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one,hydrochloride

1.2 Other means of identification

Product number	-
Other names	4-[4-(4-chlorophenyl)-4-hydroxypiperidino]-4'-fluorobutyrophenone hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1511-16-6 SDS

1511-16-6Upstream product

• 39512-49-7 4-(4-chlorophenyl)-4-hydroxypiperidine 
• 590-90-9 1-Hydroxy-3-butanone 
• 57390-39-3 γ-chloro-p-fluorobutyrophenone dimethyl ketal 

1511-16-6Downstream Products

1511-16-6Relevant articles and documents

Process for the preparation of tertiary amines

-

, (2008/06/13)

Certain tertiary amines useful as pharmaceuticals are prepared in improved yields by condensing a cyclic secondary amine with a primary alkyl halide in an aqueous medium in the presence of an acid acceptor.

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