1515-14-6Relevant articles and documents
An improved synthesis for bis(trifluoromethyl)ketene
Schwab,Sundermeyer
, p. 479 - 481 (1997)
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1,1,1,3,3,3-hexafluoro-2-methyl-2-propanol preparation method
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Paragraph 0033-0044, (2018/06/14)
The invention discloses a 1,1,1,3,3,3-hexafluoro-2-methyl-2-propanol preparation method, wherein raw materials such as trifluoroacetone and trifluoromethyl trimethylsilane are subjected to a reactionin an organic solvent in the presence of a catalyst to obtain (1,1-ditrifluoromethyl)ethoxytrimethylsilane, and a hydrolysis reaction is performed to obtain the 1,1,1,3,3,3-hexafluoro-2-methyl-2-propanol. According to the present invention, the method has advantages of high yield, low toxicity of reaction raw materials, mild reaction condition and easy operation, and is suitable for industrial production.
Hydrogen bonding between solutes in solvents octan-1-ol and water
Abraham, Michael H.,Gola, Joelle M. R.,Cometto-Muniz, J. Enrique,Acree, William E.
experimental part, p. 7651 - 7658 (2011/02/25)
The 1:1 equilibrium constants, K, for the association of hydrogen bond bases and hydrogen bond acids have been determined by using octan-1-ol solvent at 298 K for 30 acid-base combinations. The values of K are much smaller than those found for aprotic, rather nonpolar solvents. It is shown that the log K values can satisfactorily be correlated against αH 2?βH2, where αH 2 and βH2 are the 1:1 hydrogen bond acidities and basicities of solutes. The slope of the plot, 2.938, is much smaller than those for log K values in the nonpolar organic solvents previously studied. An analysis of literature data on 1:1 hydrogen bonding in water yields a negative slope for a plot of log K against αH 2?βH2, thus showing how the use of very strong hydrogen bond acids and bases does not lead to larger values of log K for 1:1 hydrogen bonding in water. It is suggested that for simple 1:1 association between monofunctional solutes in water, log K cannot be larger than about -0.1 log units. Descriptors have been obtained for the complex between 2,2,2-trifluoroethanol and propanone, and used to analyze solvent effects on the two reactants, the complex, and the complexation constant.
