151519-23-2

• 

• Basic information

  1. Product Name: 3H-1,2,4-Triazole-3-thione,2,4-dihydro-5-methyl-4-(1-methylethyl)-(9CI)
  2. Synonyms: 3H-1,2,4-Triazole-3-thione,2,4-dihydro-5-methyl-4-(1-methylethyl)-(9CI)
  3. CAS NO:151519-23-2
  4. Molecular Formula: C₆H₁₁N₃S
  5. Molecular Weight: 157.24
  6. EINECS: N/A
  7. Product Categories: ISOPROPYL
  8. Mol File: 151519-23-2.mol
  9. Article Data: 2

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: /
  5. Density: N/A
  6. Refractive Index: N/A
  7. Storage Temp.: N/A
  8. Solubility: N/A
  9. CAS DataBase Reference: 3H-1,2,4-Triazole-3-thione,2,4-dihydro-5-methyl-4-(1-methylethyl)-(9CI)(CAS DataBase Reference)
  10. NIST Chemistry Reference: 3H-1,2,4-Triazole-3-thione,2,4-dihydro-5-methyl-4-(1-methylethyl)-(9CI)(151519-23-2)
  11. EPA Substance Registry System: 3H-1,2,4-Triazole-3-thione,2,4-dihydro-5-methyl-4-(1-methylethyl)-(9CI)(151519-23-2)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 151519-23-2(Hazardous Substances Data)

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• Article

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• 3H-1,2,4-Triazole-3-thione,2,4-dihydro-5-methyl-4-(1-methylethyl)-

  Cas No: 151519-23-2

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• Hangzhou J&H Chemical Co., Ltd.
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• 3H-1,2,4-Triazole-3-thione,2,4-dihydro-5-methyl-4-(1-methylethyl)-

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• Henan Tianfu Chemical Co., Ltd.
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• 3H[1,2,4]TRIAZOLE-3-THIONE,2,4-DIHYDRO-5-METHYL-4-(ISOPROPYL)-

  Cas No: 151519-23-2

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• Hangzhou Fandachem Co.,Ltd
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• 3H-1,2,4-Triazole-3-thione,2,4-dihydro-5-methyl-4-(1-methylethyl)-(9CI)

  Cas No: 151519-23-2

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151519-23-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 151519-23-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,5,1 and 9 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 151519-23:
(8*1)+(7*5)+(6*1)+(5*5)+(4*1)+(3*9)+(2*2)+(1*3)=112
112 % 10 = 2
So 151519-23-2 is a valid CAS Registry Number.

151519-23-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	4-isopropyl-5-methyl-4H-1,2,4-triazole-3-thiol

1.2 Other means of identification

Product number	-
Other names	4-isopropyl-5-methyl-4H-1,2,4-triazole-3-thiol

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:151519-23-2 SDS

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151519-23-2Relevant articles and documents

Discovery of Adamantyl Heterocyclic Ketones as Potent 11β-Hydroxysteroid Dehydrogenase Type1 Inhibitors

Su, Xiangdong,Vicker, Nigel,Thomas, Mark P.,Pradaux-Caggiano, Fabienne,Halem, Heather,Culler, Michael D.,Potter, Barry V.L.

, p. 1439 - 1451 (2011)

11β-Hydroxysteroid dehydrogenase type1 (11β-HSD1) plays a key role in converting intracellular cortisone to physiologically active cortisol, which is implicated in the development of several phenotypes of metabolic syndrome. Inhibition of 11β-HSD1 activity with selective inhibitors has beneficial effects on various conditions, including diabetes, dyslipidemia and obesity, and therefore constitutes a promising strategy to discover novel therapies for metabolic and cardiovascular diseases. A series of novel adamantyl heterocyclic ketones provides potent and selective inhibitors of human 11β-HSD1. Lead compounds display low nanomolar inhibition against human and mouse 11β-HSD1 and are selective with no activity against 11β-HSD2 and 17β-HSD1. Selected potent 11β-HSD1 inhibitors show moderate metabolic stability upon incubation with human liver microsomes and weak inhibition of human CYP450 enzymes.

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