15254-69-0Relevant articles and documents
HKOCl-2 series of green BODIPY-based fluorescent probes for hypochlorous acid detection and imaging in live cells
Hu, Jun Jacob,Wong, Nai-Kei,Gu, Qiangshuai,Bai, Xiaoyu,Ye, Sen,Yang, Dan
supporting information, p. 3544 - 3547 (2014/07/21)
A HKOCl-2 series of new fluorescent probes for hypochlorous acid (HOCl) detection in live cells is reported. The probes exhibit excellent selectivity, sensitivity, and chemostability toward HOCl. In particular, HKOCl-2b rapidly and selectively detects endogenous HOCl in both human and mouse macrophages. These probes could therefore serve as promising discovery tools to help elucidate biological functions of HOCl.
Competitive epoxidation and quinone formation in the dimethyldioxirane oxidation of diazoquinones as ambident nucleophiles
Adam, Waldemar,Hadjiarapoglou, Lazaros,Mielke, Karsten,Treiber, Alexander
, p. 5625 - 5628 (2007/10/02)
In addition to the expected dimethyldioxirane (DMD) oxidation of diazoquinones 1 to their quinones 2, the corresponding epoxy quinones 3 are formed directly and not as secondary overoxidation products of the quinones 2 since the latter are persistent towards DMD under these conditions; this novel oxidation is rationalized in terms of the ambident nucleophilic nature of the diazoquinones and corroborated by MO (AMI) calculations.