15265-28-8 Usage
Description
Palitantin is a fungal metabolite originally isolated from P. palitans. It inhibits HIV-1 integrase with IC50 values of 350 and 268 μM for 3’-processing and strand transfer activity, respectively. Palitantin has been used as a standard for dereplication of natural products.
Uses
Palitantin is an antifungal and antiprotozoal compound.
Check Digit Verification of cas no
The CAS Registry Mumber 15265-28-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,2,6 and 5 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 15265-28:
(7*1)+(6*5)+(5*2)+(4*6)+(3*5)+(2*2)+(1*8)=98
98 % 10 = 8
So 15265-28-8 is a valid CAS Registry Number.
InChI:InChI=1/C14H22O4/c1-2-3-4-5-6-7-10-8-12(16)14(18)13(17)11(10)9-15/h4-7,10-12,14-16,18H,2-3,8-9H2,1H3/b5-4+,7-6+/t10-,11+,12-,14-/m1/s1
15265-28-8Relevant articles and documents
THE BIOSYNTHESIS OF FULVIC ACID, A FUNGAL METABOLITE OF HEPTAKETIDE ORIGIN
Kurobane, Itsuo,Hutchinson, C. Richard,Vining, Leo C.
, p. 493 - 496 (2007/10/02)
Analyses of the regiochemistry of acetate incorporation into fulvic acid (2) by Penicillium brefeldianum indicates that the metabolite is biosynthesized via a heptaketide intermediate assembled as a single chain of seven C2 units rather than from two smaller polyketide chains.This information favours a route leading through common C14 intermediates to the three fungal metabolites, citromycetin, fulvic acid and fusarubin.