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15265-28-8

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15265-28-8 Usage

Description

Palitantin is a fungal metabolite originally isolated from P. palitans. It inhibits HIV-1 integrase with IC50 values of 350 and 268 μM for 3’-processing and strand transfer activity, respectively. Palitantin has been used as a standard for dereplication of natural products.

Uses

Palitantin is an antifungal and antiprotozoal compound.

Check Digit Verification of cas no

The CAS Registry Mumber 15265-28-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,2,6 and 5 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 15265-28:
(7*1)+(6*5)+(5*2)+(4*6)+(3*5)+(2*2)+(1*8)=98
98 % 10 = 8
So 15265-28-8 is a valid CAS Registry Number.
InChI:InChI=1/C14H22O4/c1-2-3-4-5-6-7-10-8-12(16)14(18)13(17)11(10)9-15/h4-7,10-12,14-16,18H,2-3,8-9H2,1H3/b5-4+,7-6+/t10-,11+,12-,14-/m1/s1

15265-28-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R,3R,5S,6R)-5-[(1E,3E)-hepta-1,3-dienyl]-2,3-dihydroxy-6-(hydroxymethyl)cyclohexan-1-one

1.2 Other means of identification

Product number -
Other names Palitantin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15265-28-8 SDS

15265-28-8Downstream Products

15265-28-8Related news

Asymmetric synthesis of palitantin (cas 15265-28-8) from the (5R)-tert-butyldimethylsiloxy-2-cyclohexenone08/04/2019

(+)-Palitantin (2) has been synthesized in 25% overall yield from the (5R)-tert-butyldimethylsiloxy-2-cyclohexenone [(R)-1] where a remarkable diastereoselective cat. OsO4 cis-dihydroxylation of (R)-1 furnished the precursor of the optically pure (5R,6R)-bis-trimethylsiloxy 2-cyclohexenone (7) w...detailed

Asymmetric synthesis of palitantin (cas 15265-28-8) by an enzymatic and organocatalytic approach08/02/2019

The natural enantiomer of the fungal metabolite (+)-palitantin has been synthesized by adopting a chemoenzymatic and organocatalytic approach. Lipase catalyzed kinetic resolution, Sharpless asymmetric dihydroxylation and organocatalytic asymmetric hydroxymethylation are the key steps involved in...detailed

15265-28-8Relevant articles and documents

THE BIOSYNTHESIS OF FULVIC ACID, A FUNGAL METABOLITE OF HEPTAKETIDE ORIGIN

Kurobane, Itsuo,Hutchinson, C. Richard,Vining, Leo C.

, p. 493 - 496 (2007/10/02)

Analyses of the regiochemistry of acetate incorporation into fulvic acid (2) by Penicillium brefeldianum indicates that the metabolite is biosynthesized via a heptaketide intermediate assembled as a single chain of seven C2 units rather than from two smaller polyketide chains.This information favours a route leading through common C14 intermediates to the three fungal metabolites, citromycetin, fulvic acid and fusarubin.

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