153-91-3 Usage
Description
A-METHYL-L-TRYPTOPHAN, also known as α-methyl-DL-tryptophan, is an amino acid derivative with the chemical properties of a white to off-white powder. It is a significant compound in the field of medical research and pharmaceutical development due to its unique interactions with specific amino acid transporters.
Uses
Used in Pharmaceutical Industry:
A-METHYL-L-TRYPTOPHAN is used as a blocker for ATBo, an amino acid transporter that is upregulated in cancer cells. Its application is crucial for targeting cancer cells more effectively and potentially limiting the growth and proliferation of tumors by disrupting the transport of essential amino acids.
A-METHYL-L-TRYPTOPHAN is also used as a substrate or non-transported inhibitor of the amino acid transporter PAT2 (slc36a2). This dual functionality allows for further research and development in understanding the role of amino acid transport in various biological processes and potential therapeutic applications.
Biochem/physiol Actions
α-methyl-DL-tryptophan is a blocker of ATBo, an amino acid transporter whose expression is upregulated in cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 153-91-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,5 and 3 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 153-91:
(5*1)+(4*5)+(3*3)+(2*9)+(1*1)=53
53 % 10 = 3
So 153-91-3 is a valid CAS Registry Number.