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15313-37-8

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  • 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-methyl-3,8-dihydropurin-6-one

    Cas No: 15313-37-8

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15313-37-8 Usage

Uses

7-Methylguanosine is used as a biomarker for some types of cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 15313-37-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,3,1 and 3 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 15313-37:
(7*1)+(6*5)+(5*3)+(4*1)+(3*3)+(2*3)+(1*7)=78
78 % 10 = 8
So 15313-37-8 is a valid CAS Registry Number.

15313-37-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-METHYLGUANOSINE

1.2 Other means of identification

Product number -
Other names N7-methylguanosine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15313-37-8 SDS

15313-37-8Downstream Products

15313-37-8Related news

Adsorption stages and association of 1-methylguanosine and 7-METHYLGUANOSINE (cas 15313-37-8) in solutions of varying pH at charged interfaces08/12/2019

A systematic study on the adsorption and association of 1-methylguanosine and 7-methylguanosine has been undertaken at the mercury|solution interface. The characteristic properties and adsorption parameters of the dilute and compact adsorption layers of both compounds were evaluated from the dou...detailed

Intramolecular carboxylate catalysis in the depurination of a 7-METHYLGUANOSINE (cas 15313-37-8) derivative08/09/2019

We have compared the pH-independent rates of glycosidic hydrolysis in a carboxylate-bearing 7-methylguanosine derivative with those of a reference compound and with that of 7-methylguanosine itself. A syn-oriented carboxylate group affords catalysis in the hydrolysis reaction, although the insta...detailed

Artificial receptors for the extraction of nucleoside metabolite 7-METHYLGUANOSINE (cas 15313-37-8) from aqueous media made by molecular imprinting08/07/2019

A series of imprinted polymers targeting nucleoside metabolites, prepared using a template analogue approach, are presented. These were prepared following selection of the optimum functional monomer by solution association studies using 1H NMR titrations whereby methacrylic acid was shown to be ...detailed

Synthesis of N2-modified 7-METHYLGUANOSINE (cas 15313-37-8) 5′-monophosphates as nematode translation inhibitors08/06/2019

Preparative scale synthesis of 14 new N2-modified mononucleotide 5′ mRNA cap analogues was achieved. The key step involved use of an SNAr reaction with protected 2-fluoro inosine and various primary and secondary amines. The derivatives were tested in a parasitic nematode, Ascaris suum, cell-fr...detailed

15313-37-8Relevant articles and documents

Syntheses of [6,7-15N]-adenosine, [6,7-15N]-2'-deoxyadenosine, and [7-15N]-hypoxanthine

Pagano,Lajewski,Jones

, p. 11669 - 11672 (1995)

We have developed a high-yield route for the synthesis of [7-15N]-hypoxanthine in four steps in an overall yield of 81%. This procedure uses [15N]-sodium nitrite as the 15N source and an inexpensive pyrimidine to provide an economical route to this useful 15N-labeled intermediate. Conversion to [7-15N]-6-chloropurine followed by enzymatic transglycosylation gives the corresponding ribo- and 2'-deoxyribonucleosides. Ammonolysis of the 6-chloro moiety to give the [6,7-15N]-labeled nucleosides is effected simply and in high yield using 2 equiv of [15N]-ammonium chloride and 3 equiv of potassium bicarbonate.

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