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153773-82-1

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  • 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-(((3S,5S)-5-(((3-ca rboxyphenyl)amino)carbonyl)-3-pyrrolidinyl)thio)-6-((1R)-1-hydroxyethy l)-4-methyl-7-oxo-, monosodium salt, (4R,5S,6S)-

    Cas No: 153773-82-1

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  • 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-(((3S,5S)-5-(((3-ca rboxyphenyl)amino)carbonyl)-3-pyrrolidinyl)thio)-6-((1R)-1-hydroxyethy l)-4-methyl-7-oxo-, monosodium salt, (4R,5S,6S)-

    Cas No: 153773-82-1

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153773-82-1 Usage

Uses

Ertapenem sodium has been used as a carbapenem in the NitroSpeed-Carba NP test in minimum inhibitory concentration (MIC) testing for differentiation of carbapenemases in Enterobacterales and Pseudomonas aeruginosa. It has also been used as an antibiotic to study its effects on the survival of septic mice.

Definition

ChEBI: The monosodium salt of ertapenem. It is used for the treatment of moderate to severe susceptible infections including intra-abdominal and acute gynaecological infections, pneumonia, and infections of the skin and of the urinary tract. It is more stable to renal dehydropeptidase I tham imipenem, and so unlike imipenem, its use with cilastatin, which inhibits the enzyme, is not required.

Biochem/physiol Actions

Ertapenem is a broad spectrum carbopenem antibiotic. Ertapenem is active against both gram-positive and gram-negative bacteria. Ertapenem shows an extended duration of action in vivo due to its reversible binding to serum protein.

Check Digit Verification of cas no

The CAS Registry Mumber 153773-82-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,7,7 and 3 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 153773-82:
(8*1)+(7*5)+(6*3)+(5*7)+(4*7)+(3*3)+(2*8)+(1*2)=151
151 % 10 = 1
So 153773-82-1 is a valid CAS Registry Number.
InChI:InChI=1/C22H25N3O7S.Na/c1-9-16-15(10(2)26)20(28)25(16)17(22(31)32)18(9)33-13-7-14(23-8-13)19(27)24-12-5-3-4-11(6-12)21(29)30;/h3-6,9-10,13-16,23,26H,7-8H2,1-2H3,(H,24,27)(H,29,30)(H,31,32);/q;+1/p-1/t9-,10-,13+,14+,15-,16-;/m1./s1

153773-82-1 Well-known Company Product Price

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  • Sigma

  • (SML1238)  Ertapenem sodium  ≥90% (HPLC)

  • 153773-82-1

  • SML1238-10MG

  • 983.97CNY

  • Detail
  • Sigma

  • (SML1238)  Ertapenem sodium  ≥90% (HPLC)

  • 153773-82-1

  • SML1238-50MG

  • 3,970.98CNY

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153773-82-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name ertapenem sodium

1.2 Other means of identification

Product number -
Other names 2',4',6',3,4-PENTAHYDROXYDIHYDROCHALCONE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:153773-82-1 SDS

153773-82-1Downstream Products

153773-82-1Relevant articles and documents

A double protection of the border he south cultivates the crystal and its preparation process

-

Paragraph 0067; 0068, (2017/08/25)

The present invention relates to the technical field of pharmaceutical intermediate synthesis, particularly to the technical field of a crystal form and a preparation process of an ertapenem intermediate, particularly to a crystal form and a preparation process of double-protection ertapenem, wherein the characteristic peaks of the double-protection group ertapenem crystal form exist when the 2[theta] angle is 5.7+/-0.2 DEG, 8.6+/-0.2 DEG, 12.8+/-0.2 DEG, 14.3+/-0.2 DEG, 15.8+/-0.2 DEG, 16.7+/-0.2 DEG, and 18.0+/-0.2 DEG.

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