159495-64-4Relevant articles and documents
Thiosugars VI: A simple stereoselective approach to (1→3)-3-S-thiodisaccharides from levoglucosenone
Witczak, Zbigniew J.,Kaplon, Peter,Kolodziej, Mark
, p. 521 - 530 (2002)
A new stereoselective synthesis of (1→3)-3-S-thiodisaccharides is described. Levoglucosenone-derived chiral building blocks produced by the selenium-mediated iodination at C-3 afforded 3-iodoketones in moderate yield. Iodine displacement with sulfur nucleophiles (1-thiols) resulted in 3-thiodisaccharides. Following reduction of the C-2 keto function constituted a new two-step general approach to these biologically important thiosugars.
α-(1->2)-, α-(1->3)-, and α-(1->6)-Linked thioglycosidic disaccharides: syntheses and anti-HIV testing of thiokojibiose octaacetate, thionigerose, and thioisomaltose
Comber, Robert N.,Friedrich, Joyce D.,Dunshee, David A.,Petty, Sandra L.,Secrist, John A.
, p. 245 - 256 (2007/10/02)
The syntheses of several α-linked thioglycosidic disaccharides are described, including thiokojibiose octaacetate (1), thionigerose (2), and thioisomaltose (3).The title compounds were synthesized by coupling 2,3,4,6-tetra-O-acetyl-1-S-acetyl-1-thio-α-D-g
