159589-71-6 Usage
Description
2-(2-Methyl-1H-imidazol-1-yl)benzoic acid is a chemical compound characterized by the molecular formula C11H10N2O2. It is a derivative of benzoic acid, featuring an imidazole ring that contributes to its unique chemical properties and potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
2-(2-Methyl-1H-imidazol-1-yl)benzoic acid is utilized as a key intermediate in the synthesis of drugs targeting the imidazoline receptor. Its presence in these drugs allows for modulation of the receptor's activity, which can have therapeutic effects on certain medical conditions.
Used in Treatment of Neurological Disorders:
In the medical field, 2-(2-Methyl-1H-imidazol-1-yl)benzoic acid is studied for its potential role in treating neurological disorders. The imidazole ring may interact with specific receptors or pathways in the nervous system, offering a new avenue for therapeutic intervention.
Used in Treatment of Cardiovascular Diseases:
2-(2-Methyl-1H-imidazol-1-yl)benzoic acid is also being investigated for its possible applications in cardiovascular medicine. Its effects on imidazoline receptors could have implications for the regulation of blood pressure and other cardiovascular functions.
Used as a Building Block in Organic Synthesis:
Beyond its direct applications, 2-(2-Methyl-1H-imidazol-1-yl)benzoic acid serves as a valuable building block in the development of new organic molecules with potential biological activity. Its structural features make it a versatile component in the creation of novel compounds for research and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 159589-71-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,9,5,8 and 9 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 159589-71:
(8*1)+(7*5)+(6*9)+(5*5)+(4*8)+(3*9)+(2*7)+(1*1)=196
196 % 10 = 6
So 159589-71-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H10N2O2/c1-8-12-6-7-13(8)10-5-3-2-4-9(10)11(14)15/h2-7H,1H3,(H,14,15)
159589-71-6Relevant articles and documents
Preparation of highly potent and selective non-peptide antagonists of the arginine vasopressin V1A receptor by introduction of a 2-ethyl-1H-1-imidazolyl group
Shimada, Yoshiaki,Akane, Hiroaki,Taniguchi, Nobuaki,Matsuhisa, Akira,Kawano, Noriyuki,Kikuchi, Kazumi,Yatsu, Takeyuki,Tahara, Atsuo,Tomura, Yuichi,Kusayama, Toshiyuki,Wada, Koh-Ichi,Tsukada, Junko,Tsunoda, Takashi,Tanaka, Akihiro
, p. 764 - 769 (2007/10/03)
To find a new series of arginine vasopressin (AVP) V1A receptor antagonists, the influence of the 2-phenyl group of 2-phenyl-4′-[(2,3,4,5- tetrahydro-1H-1-benzazepin-1-yl)carbonyl]benzanilide (7) was investigated. Replacement of the 2-phenyl group by a 2-ethyl-1H-imidazol-1-yl group was effective in yielding a V1A-selective compound. Moreover, this imidazolyl group was introduced in the same position in YM-35471 (6), and further studies of these compounds were performed. Consequently, we found that the (Z)-4′-({4,4-difluoro-5-[(N-cyclo-propylcarbamoyl) methylene]-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl}carbonyl)-2-(2-ethyl-1H-1- imidazol-1-yl)benzanilide (9f) exhibited highly potent affinity and selectivity, and was the most potent antagonist for the V1A receptor among our compounds. The synthesis and pharmacological evaluation of these compounds are described in this paper
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