159981-07-4Relevant articles and documents
4'-Thio-RNA: Synthesis, base pairing properties and interaction with dimerization initiation site of HIV-1
Dukhan, David,De Valette, Florence,Marquet, Roland,Ehresmann, Bernard,Ehresmann, Chantal,Morvan, Francois,Barascut, Jean-Louis,Imbach, Jean-Louis
, p. 1423 - 1424 (1999)
In the present paper, we describe the synthesis of a modified 9-mer oligonucleotide, 4'-S-r(UGUGCACCU) containing for the first time 4'-thio- guanosine units. This modified 9-mer was found to inhibit in vitro genomic RNA dimerization as well as the wild type RNA.
4'-Thio-β-D-oligoribonucleotides: Nuclease resistance and hydrogen bonding properties
Leydier,Bellon,Barascut,Imbach
, p. 1027 - 1030 (2007/10/02)
The syntheses and the study of nuclease resistance and hydrogen bonding of modified oligoribonucleotides, i.e. 4'-thio-β-D-oligoribonucleotides (4'-S-RNA), are reported.