160096-59-3

• 

• Basic information

  1. Product Name: VERATRYLCURCUMINOID
  2. Synonyms: VERATRYLCURCUMINOID;Dimethoxycurcumin;(1E,4Z,6E)-1,7-bis(3,4-dimethoxyphenyl)-5-hydroxyhepta-1,4,6-trien-3-one;Dimethoxycurcumin(DiMC);Dimethoxycurcumin(DMC)
  3. CAS NO:160096-59-3
  4. Molecular Formula: C₂₃H₂₄O₆
  5. Molecular Weight: 396.43306
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 160096-59-3.mol
  9. Article Data: 15

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: 587.007°C at 760 mmHg
  3. Flash Point: 254.399°C
  4. Appearance: /
  5. Density: 1.169g/cm³
  6. Vapor Pressure: 0mmHg at 25°C
  7. Refractive Index: 1.585
  8. Storage Temp.: N/A
  9. Solubility: N/A
  10. CAS DataBase Reference: VERATRYLCURCUMINOID(CAS DataBase Reference)
  11. NIST Chemistry Reference: VERATRYLCURCUMINOID(160096-59-3)
  12. EPA Substance Registry System: VERATRYLCURCUMINOID(160096-59-3)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 160096-59-3(Hazardous Substances Data)

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• SDS
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• Article

160096-59-3 Suppliers

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• Hot Sell Factory Supply Raw Material CAS 160096-59-3 ,Dimethoxycurcumin

  Cas No: 160096-59-3

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• Wuhan Han Sheng New Material Technology Co.，Ltd
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• VERATRYLCURCUMINOID CAS:160096-59-3

  Cas No: 160096-59-3

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• 1,6-Heptadiene-3,5-dione,1,7-bis(3,4-dimethoxyphenyl)-, (1E,6E)-

  Cas No: 160096-59-3

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• 1,6-Heptadiene-3,5-dione,1,7-bis(3,4-dimethoxyphenyl)-, (1E,6E)-

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• VERATRYLCURCUMINOID

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• USD $ 10.0-100.0 / Kilogram

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• 1,6-Heptadiene-3,5-dione,1,7-bis(3,4-dimethoxyphenyl)-, (1E,6E)-

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• USD $ 100.0-100.0 / Gram

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• Dimethoxycurcumin

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• VERATRYLCURCUMINOID

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160096-59-3 Usage

Description

VERATRYLCURCUMINOID is a compound derived from curcumin, a natural polyphenol found in the spice turmeric. It possesses anti-inflammatory, antioxidant, and immunomodulatory properties, making it a potential candidate for various therapeutic applications.

Uses

Used in Pharmaceutical Industry:
VERATRYLCURCUMINOID is used as an anti-inflammatory agent for its ability to inhibit mitogen-induced proliferation of CD4+ T cells, CD8+ T cells, and B cells, as well as the secretion of various cytokines such as IL-2, IL-4, IL-6, and IFN-γ in isolated human lymphocytes.
VERATRYLCURCUMINOID is also used as an antioxidant agent for its ability to inhibit LPS-induced nitric oxide (NO) production and expression of inducible nitric oxide synthase (iNOS) in RAW 264.7 cells, as well as to inhibit hemolysis of isolated human red blood cells (RBCs) induced by AAPH.
Used in Cancer Treatment:
VERATRYLCURCUMINOID is used as an anticancer agent for its effectiveness at suppressing HCT116 tumor cells, which is more potent than its parent compound, curcumin. It may have potential applications in the development of novel drug delivery systems to enhance its bioavailability and therapeutic outcomes in cancer treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 160096-59-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,0,0,9 and 6 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 160096-59:
(8*1)+(7*6)+(6*0)+(5*0)+(4*9)+(3*6)+(2*5)+(1*9)=123
123 % 10 = 3
So 160096-59-3 is a valid CAS Registry Number.

InChI:InChI=1/C23H24O6/c1-26-20-11-7-16(13-22(20)28-3)5-9-18(24)15-19(25)10-6-17-8-12-21(27-2)23(14-17)29-4/h5-14H,15H2,1-4H3/b9-5+,10-6+

160096-59-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name	Dimethoxycurcumin

1.2 Other means of identification

Product number	-
Other names	Di-O-methylchlordeoxydecarboxyphomazarin

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:160096-59-3 SDS

160096-59-3Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 123-54-6 acetylacetone 
• 458-37-7 curcumin 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 15001-27-1 O-methyldehydrozingerone 
• 39856-08-1 (E)-3,4-dimethoxycinnamic chloride 
• 111-30-8 Glutaraldehyde 

160096-59-3Downstream Products

• 55094-78-5 di-O-methyltetrahydrocurcumin 
• 52328-97-9 (1E,6E)-1,7-bis(3,4-dimethoxyphenyl)-4,4-dimethylhepta-1,6-diene-3,5-dione 
• 1226895-15-3 FLLL₃₂ 
• 52328-98-0 O,O-dimethyl-curcumin 
• 1118765-35-7 (2E,6E)-methyl-7-(3,4-dimethoxyphenyl)-4-((E)-(3,4-dimethoxyphenyl)acryloyl)-5-oxohepta-2,6-dienoate 
• 1118765-46-0 (E,E)-3,5-bis(3,4-dimethoxystyryl)isoxazole 
• 478919-25-4 (E,E)-3,5-bis(3,4-dimethoxystyryl)-1H-pyrazole 
• 1118765-36-8 (2E,6E)-ethyl-7-(3,4-dimethoxyphenyl)-4-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-oxohepta-2,6-dienoate 

160096-59-3Relevant articles and documents

Curcumin-Cu(II) Ensemble-Based Fluorescence "turn-On" Mode Sensing the Plant Defensive Hormone Salicylic Acid in Situ and in Vivo

Chen, Chong,Yang, Lin-Lin,Tang, A-Ling,Wang, Pei-Yi,Dong, Rong,Wu, Zhi-Bing,Li, Zhong,Yang, Song

, p. 4844 - 4850 (2020/05/01)

Salicylic acid (SA), a crucial, plant-derived signal molecule, is capable of launching global transcriptional reprogramming to assist plants in obtaining the systemic acquired resistance (SAR) mechanism. Thus, the accurate detection of SA will not only si

A PERSONAL CARE COMPOSITION

-

Page/Page column 16; 17, (2018/09/18)

Disclosed is a personal care composition and a method of providing antiperspirant and anti-inflammation using certain curcuminoid derivatives. The composition comprises: (i) a compound of the Formula 1 Ar-CHnCHn-X.C(R)2-X.CHnCHn-Ar (Formula 1) wherein Ar is a substituted or unsubstituted phenyl group; R is H or CH3; X is CH(OH) group or C=O group; n has the value 1 or 2; and, (ii) a topically acceptable base comprising at least 0.1% of a fragrance wherein, when n=1, the compound of (Formula 1) is 1E,6E)-1,7-bis(3,4- dimethoxyphenyl)-4,4-dimethylhepta-1,6-diene-3,5-dione (Formula 2), and when n=2, the compound of (Formula 1) is 1,7-bis(4-hydroxy-3- methoxyphenyl) heptane-3,5-diol (Formula 4) or is 1,7-bis (3,4-dimethoxyphenyl)-4,4-dimethylheptane-3,5-diol (Formula 5).

Structure activity relationship study of curcumin analogues toward the amyloid-beta aggregation inhibitor

Endo, Hitoshi,Nikaido, Yuri,Nakadate, Mamiko,Ise, Satomi,Konno, Hiroyuki

supporting information, p. 5621 - 5626 (2015/01/08)

Inhibition of the amyloid β aggregation process could possibly prevent the onset of Alzheimer's disease. In this article, we report a structure-activity relationship study of curcumin analogues for anti amyloid β aggregation activity. Compound 7, the ideal amyloid β aggregation inhibitor in vitro among synthesized curcumin analogues, has not only potent anti amyloid β aggregation effects, but also water solubility more than 160 times that of curcumin. In addition, new approaches to improve water solubility of curcumin-type compounds are proposed.

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