16143-84-3

• 

• Basic information

  1. Product Name: 3,5-BIS(TRIFLUOROMETHYL)ACETANILIDE
  2. Synonyms: N1-[3,5-DI(TRIFLUOROMETHYL)PHENYL]ACETAMIDE;3',5'-BIS(TRIFLUOROMETHYL)ACETANILIDE;3,5-BIS(TRIFLUOROMETHYL)ACETANILIDE;3,5-DI(TRIFLUOROMETHYL)ACETANILIDE;3',5'-Bis(trifluoromethyl)acetanilide 97%;3',5'-Bis(trifluoromethyl)acetanilide97%;N-(3,5-Bis(trifluoroMethyl)phenyl)acetaMide
  3. CAS NO:16143-84-3
  4. Molecular Formula: C₁₀H₇F₆NO
  5. Molecular Weight: 271.16
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 16143-84-3.mol
  9. Article Data: 10

• Chemical Properties

  1. Melting Point: 160 °C
  2. Boiling Point: 262.6°Cat760mmHg
  3. Flash Point: 112.6°C
  4. Appearance: /
  5. Density: 1.43g/cm³
  6. Vapor Pressure: 0.0108mmHg at 25°C
  7. Refractive Index: 1.445
  8. Storage Temp.: N/A
  9. Solubility: N/A
  10. PKA: 14.03±0.70(Predicted)
  11. CAS DataBase Reference: 3,5-BIS(TRIFLUOROMETHYL)ACETANILIDE(CAS DataBase Reference)
  12. NIST Chemistry Reference: 3,5-BIS(TRIFLUOROMETHYL)ACETANILIDE(16143-84-3)
  13. EPA Substance Registry System: 3,5-BIS(TRIFLUOROMETHYL)ACETANILIDE(16143-84-3)

• Safety Data

  1. Hazard Codes: Xi
  2. Statements: 36/37/38
  3. Safety Statements: 26-36/37/39
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: IRRITANT
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 16143-84-3(Hazardous Substances Data)

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16143-84-3 Suppliers

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• 3,5-bis(trifluoromethyl)acetanilide

  Cas No: 16143-84-3

• USD $ 3.0-3.0 / Kilogram

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• Dayang Chem (Hangzhou) Co.,Ltd.
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• Ality Chemical Corporation
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• 3',5'-Bis(trifluoromethyl)acetanilide

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• Hangzhou J&H Chemical Co., Ltd.
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• Hunan chemfish Pharmaceutical co.,Ltd
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• 3',5'-Bis(trifluoromethyl)acetanilide 97%

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• Hunan Russell Chemicals Technology Co.,Ltd
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• 3,5-Bis(trifluoromethyl)acetanilide 16143-84-3

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• Shenzhen Foris Technology Co. LTD
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• 3,5-BIS(TRIFLUOROMETHYL)ACETANILIDE

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• ZHEJIANG JIUZHOU CHEM CO.,LTD
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• N-[3,5-bis(trifluoromethyl)phenyl]acetamide

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• 10 Milligram

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16143-84-3 Usage

General Description

3,5-Bis(trifluoromethyl)acetanilide is a chemical compound that belongs to the class of acetanilides. It is a white solid with a molecular formula C10H8F6N2O and a molecular weight of 286.17 g/mol. 3,5-BIS(TRIFLUOROMETHYL)ACETANILIDE is commonly used as a building block in organic synthesis and pharmaceutical research. Its trifluoromethyl groups make it a valuable reagent in the synthesis of various pharmaceuticals and agrochemicals. It is also known to exhibit anti-inflammatory and analgesic properties, making it a potential candidate for drug development. Additionally, its high thermal stability and resistance to oxidation make it a valuable reagent in various chemical reactions.

Check Digit Verification of cas no

The CAS Registry Mumber 16143-84-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,1,4 and 3 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 16143-84:
(7*1)+(6*6)+(5*1)+(4*4)+(3*3)+(2*8)+(1*4)=93
93 % 10 = 3
So 16143-84-3 is a valid CAS Registry Number.

InChI:InChI=1/C10H7F6NO/c1-5(18)17-8-3-6(9(11,12)13)2-7(4-8)10(14,15)16/h2-4H,1H3,(H,17,18)

16143-84-3 Well-known Company Product Price

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• Alfa Aesar

• (A17675)  3',5'-Bis(trifluoromethyl)acetanilide, 98%   

• 16143-84-3

• 1g

• 116.0CNY

• Detail

• Alfa Aesar

• (A17675)  3',5'-Bis(trifluoromethyl)acetanilide, 98%   

• 16143-84-3

• 5g

• 466.0CNY

• Detail

16143-84-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	N-[3,5-bis(trifluoromethyl)phenyl]acetamide

1.2 Other means of identification

Product number	-
Other names	N-(3,5-bis(trifluoromethyl)phenyl)acetamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:16143-84-3 SDS

16143-84-3Upstream product

• 174824-16-9 2-bromo-3,5-bis(trifluoromethyl)-benzenamine 
• 127-19-5 N,N-dimethyl acetamide 
• 328-74-5 3,5-Bis-(trifluoromethyl)aniline 
• 75-36-5 acetyl chloride 
• 141-78-6 ethyl acetate 
• 328-75-6 1-nitro-3,5-bis(trifluoromethyl)benzene 
• 108-24-7 acetic anhydride 

16143-84-3Downstream Products

• 367-65-7 3,5-bis(trifluoromethyl)-1,2-benzenediamine 
• 1355991-91-1 (1R,2R)-N₁-(5,7-bis(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)cyclohexane-1,2-diamine 
• 1355991-56-8 (1R,2R)-N₁,N₂-bis(5,7-bis(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)cyclohexane-1,2-diamine 

16143-84-3Relevant articles and documents

AN ACTIVITY-GUIDE MAP OF ELECTROPHILE-CYSTEINE INTERACTIONS IN PRIMARY HUMAN IMMUNE CELLS

-

Paragraph 0250-0251; 0267, (2021/04/23)

Disclosed herein are methods, pharmaceutical compositions, and vaccines for modulating an immune response. Also disclosed herein are methods, pharmaceutical compositions, and vaccines for inducing an immune response.

KOtBu-Promoted Transition-Metal-Free Transamidation of Primary and Tertiary Amides with Amines

Ghosh, Tridev,Jana, Snehasish,Dash, Jyotirmayee

supporting information, p. 6690 - 6694 (2019/09/12)

This work discloses transamidation of primary and tertiary amides with a range of aryl, heteroaryl, and aliphatic amines using potassium tert-butoxide. The reaction proceeds at room temperature under transition-metal-free conditions providing secondary amides in high yields. Moreover, reaction of cyclopropyl amine with tertiary amides proceeds with ring-opening to provide a rapid access to enamides.

COMPOSITIONS AND METHODS OF MODULATING IMMUNE RESPONSE

-

Paragraph 0318; 0329; 0334, (2018/01/17)

Disclosed herein are methods, pharmaceutical compositions, and vaccines for modulating an immune response. Also disclosed, herein are methods, pharmaceutical compositions, and vaccines for inducing an immune response.

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