16277-08-0

• 

• Basic information

  1. Product Name: Proline, 2-methyl-, ethyl ester, L- (8CI)
  2. Synonyms: Proline, 2-methyl-, ethyl ester, L- (8CI);L-Proline, 2-Methyl-, ethyl ester
  3. CAS NO:16277-08-0
  4. Molecular Formula: C8H15NO2
  5. Molecular Weight: 157.2102
  6. EINECS: N/A
  7. Product Categories: PYRROLE
  8. Mol File: 16277-08-0.mol
  9. Article Data: 2

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: /
  5. Density: N/A
  6. Refractive Index: N/A
  7. Storage Temp.: N/A
  8. Solubility: N/A
  9. CAS DataBase Reference: Proline, 2-methyl-, ethyl ester, L- (8CI)(CAS DataBase Reference)
  10. NIST Chemistry Reference: Proline, 2-methyl-, ethyl ester, L- (8CI)(16277-08-0)
  11. EPA Substance Registry System: Proline, 2-methyl-, ethyl ester, L- (8CI)(16277-08-0)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 16277-08-0(Hazardous Substances Data)

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• SDS
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• Downstream Products
• Article

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16277-08-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 16277-08-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,2,7 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 16277-08:
(7*1)+(6*6)+(5*2)+(4*7)+(3*7)+(2*0)+(1*8)=110
110 % 10 = 0
So 16277-08-0 is a valid CAS Registry Number.

16277-08-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	ethyl L-methylprolinate

1.2 Other means of identification

Product number	-
Other names	L-Proline, 2-methyl-, ethyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:16277-08-0 SDS

16277-08-0Upstream product

• 3082-75-5 L-Alanine ethyl ester 
• 1227635-82-6 ethyl N-benzyloxycarbonyl-(2S)-methylprolinate 

16277-08-0Downstream Products

16277-08-0Relevant articles and documents

Preparation method of veliparib

-

Paragraph 0037-0038, (2020/08/12)

The invention discloses a preparation method of veliparib, which comprises the following steps: by using readily available L-alanine ethyl ester as a raw material, carrying out imidization, cyclization reduction and hydrolysis reaction to obtain a key chiral intermediate that is (R)-2-methylpyrrolidine-2-carboxylic acid, and carrying out one-step condensation on the intermediate to obtain the target compound veliparib. The method has the characteristics of easily available raw materials, mild conditions, simple process, safety, environmental protection and the like, and is suitable for industrial production.

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