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163299-43-2

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163299-43-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 163299-43-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,3,2,9 and 9 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 163299-43:
(8*1)+(7*6)+(6*3)+(5*2)+(4*9)+(3*9)+(2*4)+(1*3)=152
152 % 10 = 2
So 163299-43-2 is a valid CAS Registry Number.

163299-43-2Relevant articles and documents

Compounds enhancing antitumor activity of other cytotoxic agents

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, (2008/06/13)

This invention relates to certain heterocyclic compounds and their pharmaceutically acceptable salts, which are useful for sensitizing multidrug-resistant tumor cells to anticancer agents and multidrug resistant forms of malaria, tuberculosis, leishmania and amoebic dysentery to chemotherapeutants. The compounds and their pharmaceutically acceptable salts are also inhibitors of the active drug transport capability of P-glycoprotein which is encoded by the human MDR1 gene, as well as of certain other related ATP-binding-cassette transporters from eukaryotic and prokaryotic organisms (e.g., pfmdr from Plasmodium falciprum, and murine mdr1 and mdr3 gene products).

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