16587-52-3Relevant articles and documents
Synthesis method of substituted dibenzothiophene compound
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, (2021/03/30)
The invention belongs to the technical field of organic synthesis, and particularly discloses a synthesis method of a substituted dibenzothiophene compound. The method comprises the following steps: reacting halogenated substituted biphenyl with an organic strong base at a low temperature, reacting with ethanedithiol to obtain a high-purity key intermediate mercaptobiphenyl, and carrying out a coupling reaction under the action of a catalyst to obtain the substituted dibenzothiophene compound. The method provided by the invention has the advantages of low raw material cost, mild reaction conditions, short reaction time, simple post-treatment, single reaction product, few byproducts, no impurity difficult to remove, simple process operation, easy obtaining of high-purity products, suitability for large-scale production of the process and the like.
Synthesis of Benzo[b]thiophenes through Rhodium-Catalyzed Three-Component Reaction using Elemental Sulfur
Moon, Sanghun,Kato, Moena,Nishii, Yuji,Miura, Masahiro
supporting information, p. 1669 - 1673 (2020/03/23)
A benzo[b]thiophene synthesis by Rh-catalyzed three-component coupling reaction of arylboronic acids, alkynes, and elemental sulfur (S8) is developed. A notable feature of this protocol is that the thienannulation (thiophene annulation) proceeds with high regioselectivity via the sequential alkyne insertion, C?H activation, and then sulfur atom transfer to the metallacycle intermediate. In a similar manner, dibenzothiophenes can be synthesized from the parent biarylboronic acids and S8. (Figure presented.).
Cyclization of 2-Biphenylthiols to Dibenzothiophenes under PdCl2/DMSO Catalysis
Zhang, Tao,Deng, Guigang,Li, Hanjie,Liu, Bingxin,Tan, Qitao,Xu, Bin
supporting information, p. 5439 - 5443 (2018/09/13)
A palladium-catalyzed synthesis of dibenzothiophenes from 2-biphenylthiols is described. This highly efficient reaction employs a simple PdCl2/DMSO catalytic system, in which PdCl2 is the sole metal catalyst and DMSO functions as an oxidant and solvent. This transformation has broad substrate scope and operational simplicity and proceeds in high yield. The synthetic utility was demonstrated by the facile synthesis of helical dinapthothiophene 3 and an eminent organic semiconductor DBTDT 4. Importantly, highly strained trithiasumanene 5, a buckybowl of considerable synthetic challenge, was observed under this catalytic system.
