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16610-63-2

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16610-63-2 Usage

Description

LAURYL ALCOHOL DIPHOSPHONIC ACID is a phosphonic acid derivative characterized by a long hydrophobic chain, which serves as a corrosion inhibitor and chelating agent in various industrial applications. Its unique structure allows it to effectively prevent and control scale deposits and corrosion in water systems, making it a valuable component in maintaining clean and protected equipment.

Uses

Used in Industrial Water Treatment:
LAURYL ALCOHOL DIPHOSPHONIC ACID is used as a corrosion inhibitor and chelating agent for preventing and controlling scale deposits and corrosion in water systems. Its hydrophobic chain and phosphonic acid properties make it highly effective in this application.
Used in Oilfield Applications:
In the oilfield industry, LAURYL ALCOHOL DIPHOSPHONIC ACID is utilized as a corrosion inhibitor and scale control agent to protect equipment and infrastructure from the damaging effects of scale buildup and corrosion.
Used in Cleaning and Personal Care Products:
LAURYL ALCOHOL DIPHOSPHONIC ACID is used as a surfactant and detergent in various cleaning and personal care products. Its ability to form micelles and emulsify oils makes it an effective ingredient for creating foam and removing dirt and grease.
Used in Water Treatment for Equipment Protection:
LAURYL ALCOHOL DIPHOSPHONIC ACID is employed as a component in water treatment systems to keep equipment clean and protected against scale and corrosion. Its properties help maintain the efficiency and longevity of water systems and associated equipment.

Check Digit Verification of cas no

The CAS Registry Mumber 16610-63-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,6,1 and 0 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 16610-63:
(7*1)+(6*6)+(5*6)+(4*1)+(3*0)+(2*6)+(1*3)=92
92 % 10 = 2
So 16610-63-2 is a valid CAS Registry Number.

16610-63-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (1-hydroxydodecane-1,1-diyl)diphosphonic acid

1.2 Other means of identification

Product number -
Other names dodecane-1-hydroxy-1,1-bisphosphonate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:16610-63-2 SDS

16610-63-2Synthetic route

n-dodecanoyl chloride
112-16-3

n-dodecanoyl chloride

(1-hydroxydodecane-1,1-diyl)diphosphonic acid
16610-63-2

(1-hydroxydodecane-1,1-diyl)diphosphonic acid

Conditions
ConditionsYield
Stage #1: n-dodecanoyl chloride With tris(trimethylsilyl) phosphite at 25℃;
Stage #2: In methanol at 25℃; for 1h;
97%
lauric acid
143-07-7

lauric acid

(1-hydroxydodecane-1,1-diyl)diphosphonic acid
16610-63-2

(1-hydroxydodecane-1,1-diyl)diphosphonic acid

Conditions
ConditionsYield
Stage #1: lauric acid With phosphorus(III) oxide In water at 100 - 135℃; for 2h; Inert atmosphere;
Stage #2: With water at 140℃; for 1.33333h;
84.2%
With P4O6 heating; Yield given;
Stage #1: lauric acid With phosphonic Acid; methanesulfonic acid; phosphorus trichloride at 65℃;
Stage #2: With water Heating;
With methanesulfonic acid; phosphorous acid; phosphorus trichloride at 90℃; for 16h;
With methanesulfonic acid; phosphorous acid; phosphorus trichloride at 90℃; for 16h;
n-dodecanoyl chloride
112-16-3

n-dodecanoyl chloride

tris(trimethylsilyl) phosphite
1795-31-9

tris(trimethylsilyl) phosphite

(1-hydroxydodecane-1,1-diyl)diphosphonic acid
16610-63-2

(1-hydroxydodecane-1,1-diyl)diphosphonic acid

Conditions
ConditionsYield
Stage #1: n-dodecanoyl chloride; tris(trimethylsilyl) phosphite at -5 - 20℃; for 2h; Inert atmosphere;
Stage #2: With methanol
82%
(1-hydroxydodecane-1,1-diyl)diphosphonic acid
16610-63-2

(1-hydroxydodecane-1,1-diyl)diphosphonic acid

alpha cyclodextrin
10016-20-3

alpha cyclodextrin

C36H60O30*C12H28O7P2

C36H60O30*C12H28O7P2

Conditions
ConditionsYield
In aq. phosphate buffer at 24.84℃; pH=6.5;
(1-hydroxydodecane-1,1-diyl)diphosphonic acid
16610-63-2

(1-hydroxydodecane-1,1-diyl)diphosphonic acid

β‐cyclodextrin
7585-39-9

β‐cyclodextrin

C42H70O35*C12H28O7P2

C42H70O35*C12H28O7P2

Conditions
ConditionsYield
In aq. phosphate buffer at 24.84℃; pH=6.5;

16610-63-2Downstream Products

16610-63-2Relevant articles and documents

A mild and efficient one-pot synthesis of 1-hydroxymethylene-1,1-bisphosphonic acids. Preparation of new tripod ligands

Lecouvey, Marc,Mallard, Isabelle,Bailly, Théodorine,Burgada, Ramon,Leroux, Yves

, p. 8475 - 8478 (2001)

A simple and efficient one-pot procedure for synthesis of 1-hydroxymethylene-1,1-bisphosphonic acids by reaction of acyl chlorides and tris(trimethylsilyl)phosphite is described. This method was applied to the synthesis of new phosphonated chelating tripod ligands.

Cyclodextrins: A promising drug delivery vehicle for bisphosphonate

Monteil, Maelle,Lecouvey, Marc,Landy, David,Ruellan, Steven,Mallard, Isabelle

, p. 285 - 293 (2016/09/23)

Bisphosphonates are well established pharmaceutical drugs with wide applications in medicine. Nevertheless, the side chain and the nature of phosphorous groups could induce a poor aqueous solubility and act on their bioavailability. At the same time, cyclodextrins are cage molecules that facilitate transport of hydrophobic molecules to enhance the intestinal drug absorption of these molecules by forming inclusion complexes. Here we demonstrate that cyclodextrins could be used as a bisphosphonate carrier. The formation of cyclodextrins-bisphosphonate complexes was characterized by 1D and 2D NMR spectroscopy, Isothermal Titration Calorimetry and UV–vis spectroscopy. The results revealed that only the side chain of bisphosphonate was involved in the inclusion phenomenon and its length was a crucial parameter in the control of affinity. Findings from this study suggest that cyclodextrin will be a useful carrier for bisphosphonates.

Bisphosphonates as inhibitors of acid sphingomyelinase

-

Page/Page column 8-10, (2011/04/14)

The present invention refers to bisphosphonate and phosphonate/phosphate compounds of Formulae I and II and its use as inhibitors of aSMase enzyme activity.

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