16709-86-7Relevant articles and documents
Free-Radical Cyclization in the Synthesis of a 1-Aza-5-silabicyclononan-9-one, a Silicon-Containing β-Lactam
Altamura, Maria,Giammaruco, Maria,Taddei, Maurizio,Ulivi, Paola
, p. 8403 - 8406 (1995)
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AMINOMERCURATION-DEMERCURATION OF DIMETHYL(CHLOROALKYL)ALKENYLSILANES AS A ROUTE TO AZASILACYCLOALKANES
Voronkov, M. G.,Kirpichenko, S. V.,Abrosimova, A. T.,Albanov, A. I.,Keiko, V. V.,Lavrent'yev, V. I.
, p. 159 - 168 (2007/10/02)
3,3-Dimethyl-1-phenyl-1-aza-3-silacyclopentane and 3,3,5-trimethyl-1-phenyl-1-aza-3-silacyclopentane were obtained by the reaction of dimethyl(chloromethyl)vinylsilane and dimethyl(chloromethyl)allylsilane with aniline in THF in the presence of mercury acetate followed by reduction with sodium borohydride.Aminomercuration-demercuration of dimethyl(3-chloropropyl)vinylsilane and dimethyl(3-chloropropyl)allylsilane results in the corresponding 3-chloropropylphenylaminoalkyl derivatives.Dimethyl(3-chloropropyl)(2-phenylaminopropyl)silane undergoes cyclization under the same reaction conditions giving 2,4,4-trimethyl-1-phenyl-1-aza-4-silacycloheptane in low yield.Competitive nucleophilic substitution of the chloroalkyl group of initial silanes by aniline affords dimethyl(phenylaminoalkyl)alkenylsilanes.
