167824-58-0 Usage
General Description
The chemical compound (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1-(3-hydroxybenzyl)-3-(5-hydroxypentyl)-1,3-diazepan-2-one is a complex organic molecule with a diazepan ring structure. It contains multiple hydroxyl groups, making it a polyhydroxy compound. It also contains a benzyl group and a 3-hydroxybenzyl group, as well as a 5-hydroxypentyl group, all of which contribute to its overall structure and reactivity. Its unique combination of functional groups gives it potential for various applications in medicinal chemistry, drug design, and chemical synthesis. However, due to its complex structure, it also presents challenges in terms of synthesis and characterization.
Check Digit Verification of cas no
The CAS Registry Mumber 167824-58-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,7,8,2 and 4 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 167824-58:
(8*1)+(7*6)+(6*7)+(5*8)+(4*2)+(3*4)+(2*5)+(1*8)=170
170 % 10 = 0
So 167824-58-0 is a valid CAS Registry Number.
167824-58-0Relevant articles and documents
Functionalized aliphatic P2/P2' analogs of HIV-1 protease inhibitor DMP323
Smallheer, Joanne M.,McHugh, Robert J.,Chang, Chong-Hwan,Kaltenbach III, Robert F.,Worley, Tabitha V.,Klabe, Ronald M.,Bacheler, Lee T.,Rayner, Marlene M.,Erickson-Viitanen, Susan,Seitz, Steven P.
, p. 1365 - 1370 (2007/10/03)
A series of analogs of HIV protease inhibitor DMP323 containing functionalized aliphatic P2/P2' groups was prepared and evaluated for HIV protease inhibition and antiviral activity in a cell-based assay. Asymmetric compounds with a 5-hydroxypentyl substituent at P2 and a benzylic substituent at P2' showed increased potency over the corresponding symmetrically substituted analogs.
