16801-56-2Relevant articles and documents
Enaminones in organic synthesis: A novel synthesis of 1,3,5-trisubstituted benzene derivatives and of 2-substituted-5-aroylpyridines
Abdel-Khalik, Mervat Mohammed,Elnagdi, Mohamed Hilmy
, p. 159 - 164 (2002)
Enaminones undergo self-condensation on reflux in acidic media yielding 1,3,5-trisubstituted benzene in very high yields. Reaction of enaminones 1a,b with ethyl propiolate affords 5-aroyl-1,3-benzene dicarboxylate derivatives.
Studies with Enaminones: The reaction of enaminones with Aminoheterocycles. A route to Azolopyrimidines, Azolopyridines and Quinolines
Almazroa, Sarah,Elnagdi, Mohamed H.,Salah El-Din, Abdellatif M.
, p. 267 - 272 (2007/10/03)
The enaminones 1b,d,f react with 4-phenyl-3-methyl-5-pyrazoleamine 3a to yield the pyrazole derivatives 4a-c that cyclised readily on reflux in pyridine solution in presence of hydrochloric acid to yield the pyrazolo[1,5-a]pyrimidines 5a-c. Similarly 3(5)