169610-52-0 Usage
Description
2,6-Dimethoxybenzylbromide, also known as DMBr, is a chemical compound characterized by the molecular formula C9H11BrO2. It is a colorless to pale yellow liquid with a strong, pungent odor. DMBr is primarily recognized for its role as a reagent in organic synthesis, where it introduces the 2,6-dimethoxybenzyl (DMB) protecting group onto various functional groups. This functionality makes it a valuable asset in medicinal chemistry, particularly for protecting hydroxyl and amine groups in pharmaceutical compounds from unwanted reactions during synthesis. Additionally, DMBr serves as a key intermediate in the production of other organic chemicals and is a staple in both academic and industrial research settings. Due to its hazardous nature, it is crucial to handle DMBr with care to avoid skin, eye, and respiratory irritation.
Uses
Used in Medicinal Chemistry:
2,6-Dimethoxybenzylbromide is used as a protecting agent for [functional groups] in pharmaceutical compounds for [preventing unwanted reactions during synthesis]. Its ability to introduce the 2,6-dimethoxybenzyl (DMB) protecting group is crucial in safeguarding hydroxyl and amine groups, ensuring the successful synthesis of complex pharmaceutical molecules.
Used in Organic Synthesis:
In the field of organic synthesis, 2,6-Dimethoxybenzylbromide is used as a reagent for [introducing the 2,6-dimethoxybenzyl (DMB) protecting group onto various functional groups]. This application is vital for the controlled synthesis of organic compounds, where the protection of certain functional groups is necessary to prevent side reactions.
Used in Academic and Industrial Research:
2,6-Dimethoxybenzylbromide is used as a key intermediate in [the production of other organic chemicals] in both academic and industrial research laboratories. Its versatility and reactivity make it an essential component in the synthesis of a wide range of organic compounds.
Used in Chemical Production:
In the chemical production industry, 2,6-Dimethoxybenzylbromide is used as an intermediate for [the synthesis of various organic chemicals]. Its role in the production process is pivotal, contributing to the creation of a diverse array of chemical products.
Safety Considerations:
When handling 2,6-Dimethoxybenzylbromide, it is used with [caution] due to its [hazardous nature], which can cause [irritation to the skin, eyes, and respiratory system]. Proper safety measures, including the use of personal protective equipment and adherence to safety protocols, are essential to minimize risks associated with its use.
Check Digit Verification of cas no
The CAS Registry Mumber 169610-52-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,9,6,1 and 0 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 169610-52:
(8*1)+(7*6)+(6*9)+(5*6)+(4*1)+(3*0)+(2*5)+(1*2)=150
150 % 10 = 0
So 169610-52-0 is a valid CAS Registry Number.
169610-52-0Relevant articles and documents
MLKL INHIBITORS
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Paragraph 0368-0369, (2018/09/26)
Purine derivatives that inhibit cellular necroptosis and/or human MLKL, pharmaceutical compositions thereof, and methods of treating an MLKL-mediated disorder with an effective amount of the compound or composition. Said MLKL-mediated disorder is pathology associated necroptosis, including ischemia-reperfusion damage, neurodegeneration, and inflammatory diseases such as acute pancreatitis, multiple sclerosis, inflammatory bowel disease, and allergic colitis.
Effect of methoxy substituents on the excited state properties of stilbene
Shinohara, Yoshihiro,Arai, Tatsuo
experimental part, p. 1500 - 1504 (2009/05/06)
Excited state properties of stilbenes having methoxy substituents at the ortho position of the phenyl ring have been studied and the remarkable methoxy substituent effect to suppress the fluorescence quantum yield depending on the number of methoxy substi
Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl)methyl]piperidines
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, (2008/06/13)
Compounds of the following structure, the corresponding N-oxides and agriculturally acceptable salts, are disclosed as effective insecticides: STR1 in which U is selected from --(CH2)n -- and ethylidene; Q is selected from hydrogen, hydroxy, sulfhydryl, and fluorine; R is STR2 in which V is selected from hydrogen, halogen, alkyl, haloalkyl, alkoxy, alkylthio, alkylsulfinyl, alkylsilyloxy, dialkylamino, cyano, nitro, hydroxy, and phenyl; Y and Z are independently selected from hydrogen and alkoxy; W and X taken together is --OCH2 CH2 O--, --CH2 C(CH3)2 O--, --OC(CH3)2 O--, or --N=C(C2 H5)O--; R1 and R2 are independently selected from phenyl substituted with halogen, alkyl, haloalkyl, haloalkoxy, alkoxyalkyl, hydroxy, arylthio, alkoxy, dialkylamino, dialkylaminosulfonyl, hydroxyalkylaminocarbonyl, alkylsulfonyloxy, and haloalkylsulfonyloxy; and n is 1, 2, or 3.
