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169674-00-4

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169674-00-4 Usage

General Description

6-Chloro-5-fluoro-1H-indole-2-carboxylic acid ethyl ester is a chemical compound with the molecular formula C12H9ClFNO2. It is an ethyl ester derivative of 6-chloro-5-fluoro-1H-indole-2-carboxylic acid, which is commonly used as an intermediate in the synthesis of pharmaceutical compounds and agrochemicals. 6-Chloro-5-fluoro-1H-indole-2-carboxylic acid ethyl ester is a yellowish-brown solid with a molecular weight of 257.65 g/mol. It is a potent inhibitor of the enzyme 3-phosphoinositide-dependent protein kinase-1 (PDK1) and is being investigated for its potential therapeutic applications in cancer treatment. Additionally, it has shown activity against various strains of bacteria, making it a promising candidate for the development of new antibiotics.

Check Digit Verification of cas no

The CAS Registry Mumber 169674-00-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,9,6,7 and 4 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 169674-00:
(8*1)+(7*6)+(6*9)+(5*6)+(4*7)+(3*4)+(2*0)+(1*0)=174
174 % 10 = 4
So 169674-00-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H9ClFNO2/c1-2-16-11(15)10-4-6-3-8(13)7(12)5-9(6)14-10/h3-5,14H,2H2,1H3

169674-00-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Methyl 6-chloro-5-fluoro-1H-indole-2-carboxylate

1.2 Other means of identification

Product number -
Other names Ethyl 6-chloro-5-fluoroindole-2-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:169674-00-4 SDS

169674-00-4Downstream Products

169674-00-4Relevant articles and documents

Indole derivative and medical application thereof

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Paragraph 0121; 0124; 0126; 0127, (2020/12/15)

The invention discloses an indole compound with FABP4/5 inhibitory activity and a preparation method and medical application of the indole compound. The indole compound is a compound of which the structural formula is shown as a formula I, and pharmaceutically acceptable salt or ester or solvate of the compound. The compound shown in the formula I is a novel FABP4/5 inhibitor and can be used for preparing medicines for preventing or treating FABP4/5 related diseases.

NOVEL 6,7-DIHYDRO-4H-PYRAZOLO[1,5-A]PYRAZINE INDOLE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)

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Page/Page column 73, (2020/05/29)

The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for mating the compounds.

NOVEL INDOLE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)

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Page/Page column 108, (2020/11/13)

The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.

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