170096-60-3Relevant articles and documents
Concise synthesis of sibrafiban and lamifiban, two non-peptide fibrinogen receptor (GP IIb/IIIa) antagonists
Chang, Meng-Yang,Chen, Shui-Tein
, p. 133 - 135 (2007/10/03)
The total synthesis of the non-peptide fibrinogen receptor antagonists, sibrafiban (1) (Ro 48-3657) and lamifiban (2) (Ro 44-9883), is described. Both contain 4-hydroxypiperidine unit and the same solid-phase synthesis method was used as a key step. Conne