170858-34-1 Usage
Description
4-(4-2-[(1S)-3,4-dihydro-1H-isochromen-1-yl]ethylpiperazin-1-yl)benzenesulfonamide methanesulfonate (1:1) is a complex organic compound with a chemical structure that includes a benzene ring, a sulfonamide group, and a piperazine ring. It is characterized by its selective D4 dopamine antagonist properties and its ability to induce c-fos gene expression in the medial prefrontal cortex, similar to the effects of Clozapine.
Uses
Used in Pharmaceutical Industry:
4-(4-2-[(1S)-3,4-dihydro-1H-isochromen-1-yl]ethylpiperazin-1-yl)benzenesulfonamide methanesulfonate (1:1) is used as a selective D4 dopamine antagonist for its low affinity at other monoamine receptors (Ki > 2000 nM). This property makes it a potential candidate for the development of new drugs targeting dopamine-related disorders.
Used in Antipsychotic Applications:
As an antipsychotic agent, 4-(4-2-[(1S)-3,4-dihydro-1H-isochromen-1-yl]ethylpiperazin-1-yl)benzenesulfonamide methanesulfonate (1:1) acts as a dopamine D4 antagonist, which can be beneficial in the treatment of various psychiatric conditions. Its ability to induce c-fos gene expression in the medial prefrontal cortex, similar to Clozapine, suggests that it may have potential therapeutic effects in treating conditions such as schizophrenia and other psychotic disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 170858-34-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,8,5 and 8 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 170858-34:
(8*1)+(7*7)+(6*0)+(5*8)+(4*5)+(3*8)+(2*3)+(1*4)=151
151 % 10 = 1
So 170858-34-1 is a valid CAS Registry Number.
170858-34-1Relevant articles and documents
Heterocyclic compounds for the treatment of CNS and cardiovascular disorders
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, (2008/06/13)
Novel aromatic bicyclic amines of formula (I) STR1 are useful in treating central nervous system disorders and cardiac arrhythmias and cardiac fibrillation.