17205-71-9 Usage
General Description
(1S)-1-C-(4-carboxythiazolidin-2-yl)-D-arabinitol, also known as CTH or 4-Carboxy-D-arabinitol, is a synthetic chemical compound that belongs to the class of thiazolidinone derivatives. It is structurally similar to the naturally occurring compound D-arabinitol, and is often used as an inhibitor of the enzyme glyoxalase I. This enzyme is involved in the detoxification of methylglyoxal, a toxic byproduct of glycolysis. CTH has been studied for its potential therapeutic applications in various conditions such as diabetes, cancer, and neurodegenerative diseases, due to its ability to modulate cellular metabolism and oxidative stress. It is also a valuable tool in biochemical research for studying the glyoxalase system and its role in cellular physiology.
Check Digit Verification of cas no
The CAS Registry Mumber 17205-71-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,2,0 and 5 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 17205-71:
(7*1)+(6*7)+(5*2)+(4*0)+(3*5)+(2*7)+(1*1)=89
89 % 10 = 9
So 17205-71-9 is a valid CAS Registry Number.
17205-71-9Relevant articles and documents
Proton and Zinc(II) Complexes of 2-(Polyhydroxyalkyl)thiazolidine-4-carboxylic acid Derivatives
Gajda, Tamas,Nagy, Laszlo,Burger, Kalman
, p. 3155 - 3160 (2007/10/02)
The protonation and zinc-ion co-ordination equilibria of 2-(polyhydroxyalkyl)thiazolidine-4-carboxylic acid derivatives have been studied by potentiometric titration in the range pH 1.5-8.In most cases the formation of complexes with a metal-to-ligand ratio of 1:2 was demonstrated, but at above pH 6 mixed-ligand complexes involving hydroxide-ion co-ordination were also observed.The protonation and complex-formation constants were shown to depend on the structure of the polyhydroxy chains.In the case of the protonation constants this is due to the rearrangement of the intramolecular hydrogen-bonding network, while the complex-formation constants depend on the conformation of the OH groups on the first carbon atoms of the polyol chains.
