172604-63-6Relevant articles and documents
Pinacol rearrangement of 3,4-dihydro-3,4-dihydroxyquinolin-2(1H)-ones: An alternative pathway to viridicatin alkaloids and their analogs
Rudolf, Ondrej,Rouchal, Michal,Lycka, Antonin,Klasek, Antonin
, p. 1905 - 1917 (2013/11/06)
3-Alkyl/aryl-3-hydroxyquinoline-2,4-diones were reduced with NaBH 4 to give cis-3-alkyl/aryl-3,4-dihydro-3,4-dihydroxyquinolin-2(1H)- ones. These compounds were subjected to pinacol rearrangement by treatment with concentrated H2SOs
NITROGEN-CONTAINING COMPOUND AND PHARMACEUTICAL COMPOSITION
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Page/Page column 421, (2011/04/13)
The present invention provides a novel diazepine compound that blocks the IKur current or the Kv1.5 channel potently and more selectively than other K+ channels. The present invention relates to a diazepine compound represented by General Formula (1) or a salt thereof, wherein R1, R2, R3, and R4 are each independently hydrogen, lower alkyl, cyclo lower alkyl or lower alkoxy lower alkyl; R2 and R3 may be linked to form lower alkylene; A1 is lower alkylene optionally substituted with one or more substituents selected from the group consisting of hydroxyl and oxo; Y1 and Y2 are each independently -N= or -CH=; and R5 is group represented by (2) wherein R6 and R7 are each independently hydrogen or organic group; R6 and R7 may be linked to form a ring together with the neighboring group -XA-N-XB-; XA and XB are each independently a bond, lower alkylene, etc.
Reactions of Diazo Compounds with Isatin and its Derivatives
Kennewell, Peter D.,Miller, David J.,Scrowston, Richard M.,Westwood, Robert
, p. 2380 - 2388 (2007/10/03)
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