17266-30-7 Usage
General Description
5-Chlorobenzo[b]thiophene-3-acetic acid is a compound that belongs to the chemical class of benzo[b]thiophenes. It consists of a benzo[b]thiophene ring with a chlorine atom at the 5th position and an acetic acid group attached to the 3rd position. 5-CHLOROBENZO[B]THIOPHENE-3-ACETIC ACID has potential pharmaceutical applications and is being studied for its anti-inflammatory and analgesic properties. It may also have use in the treatment of various diseases and conditions, such as osteoarthritis and rheumatoid arthritis. The synthesis and characterization of 5-chlorobenzo[b]thiophene-3-acetic acid are of interest in the field of medicinal chemistry and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 17266-30-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,2,6 and 6 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 17266-30:
(7*1)+(6*7)+(5*2)+(4*6)+(3*6)+(2*3)+(1*0)=107
107 % 10 = 7
So 17266-30-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H7ClO2S/c11-7-1-2-9-8(4-7)6(5-14-9)3-10(12)13/h1-2,4-5H,3H2,(H,12,13)
17266-30-7Relevant articles and documents
Orally absorbable cephalosporine antibiotics. 1. Structure-activity relationships of benzothienyl- and naphthylglycine derivatives of 7-aminodeacetoxycephalosporanic acid
Kukolja,Draheim,Pfeil,et al.
, p. 1886 - 1896 (2007/10/02)
A structure-activity relationship study of a number of orally absorbed cephalosporins together with their syntheses is described. These new cephalosporins are benzothienyl- and naphthylglycine derivatives of 7-aminodeacetoxycephalosporanic acid. Several different synthetic methods for the glycine side chains, their protection, and the final acylations are reported. Several of these analogues were more active than cephalexin both in vitro and r538w2 =(R)-7-(3-Benzothienylglycylamido)-3-methyl-3-cephem-4-carb oxylic in vivo against commonly encountered Gram-positive bacteria. (R)7-(3-Benzothienylglycylamido)-3-methyl-3-cephem-4-carboxylic acid has emerged as a potent antibacterial agent and is currently undergoing preclinical evaluation.
